U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    TSB1 tryptophan synthase beta-subunit 1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 835571, updated on 18-Sep-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    TSB1
    Official Full Name
    tryptophan synthase beta-subunit 1
    Primary source
    TAIR:AT5G54810
    Locus tag
    AT5G54810
    See related
    Araport:AT5G54810
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATTSB1; MBG8.7; MBG8_7; TRP2; TRPB; TRYPTOPHAN BIOSYNTHESIS 2; TRYPTOPHAN BIOSYNTHESIS B; tryptophan synthase beta-subunit 1
    Summary
    A.thaliana tryptophan synthase beta subunit (trpB)
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See TSB1 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    5
    Sequence:
    Chromosome: 5; NC_003076.8 (22264594..22266902, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene CTD small phosphatase-like protein Neighboring gene glucose 6-phosphate/phosphate translocator 1 Neighboring gene F-box/RNI-like superfamily protein Neighboring gene DOMON domain-containing protein / dopamine beta-monooxygenase N-terminal domain-containing protein Neighboring gene Ras-related small GTP-binding family protein

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. A gene encoding the tryptophan synthase beta subunit of Arabidopsis thaliana. Berlyn MB, et al. Proc Natl Acad Sci U S A, 1989 Jun. PMID 2734310, Free PMC Article
    2. Arabidopsis thaliana auxotrophs reveal a tryptophan-independent biosynthetic pathway for indole-3-acetic acid. Normanly J, et al. Proc Natl Acad Sci U S A, 1993 Nov 1. PMID 8234297, Free PMC Article
    3. Plant native tryptophan synthase beta 1 gene is a non-antibiotic selection marker for plant transformation. Hsiao P, et al. Planta, 2007 Mar. PMID 17039373
    4. Overexpression of Arabidopsis thaliana tryptophan synthase beta 1 (AtTSB1) in Arabidopsis and tomato confers tolerance to cadmium stress. Sanjaya, et al. Plant Cell Environ, 2008 Aug. PMID 18419734
    5. Tryptophan deficiency affects organ growth by retarding cell expansion in Arabidopsis. Jing Y, et al. Plant J, 2009 Feb. PMID 18980661

    See all (18) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Coordination of plant growth and abiotic stress responses by tryptophan synthase beta subunit 1 through modulation of tryptophan and ABA homeostasis in Arabidopsis.
      Title: Coordination of plant growth and abiotic stress responses by tryptophan synthase β subunit 1 through modulation of tryptophan and ABA homeostasis in Arabidopsis.
    2. A mutation in the TSB1 gene affects organogenesis by retarding cell expansion.
      Title: Tryptophan deficiency affects organ growth by retarding cell expansion in Arabidopsis.
    3. Overexpression of AtTSB1 in transgenic tomato also produced higher Trp synthase-beta enzyme activity than that in wild-type plants.
      Title: Overexpression of Arabidopsis thaliana tryptophan synthase beta 1 (AtTSB1) in Arabidopsis and tomato confers tolerance to cadmium stress.
    4. The TSB1 system provides a novel selection system distinct from conventional antibiotic selection systems.
      Title: Plant native tryptophan synthase beta 1 gene is a non-antibiotic selection marker for plant transformation.
    Submit: New GeneRIF Correction

    Pathways from PubChem

    Go to the top of the page

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    NM_124862.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables tryptophan synthase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables tryptophan synthase activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within indoleacetic acid biosynthetic process TAS
    Traceable Author Statement
    more info
    		 PubMed 
    acts_upstream_of_or_within response to oxidative stress IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in tryptophan biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within tryptophan biosynthetic process TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast HDA PubMed 
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in chloroplast ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    located_in chloroplast stroma HDA PubMed 
    located_in plasma membrane HDA PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    tryptophan synthase beta-subunit 1
    NP_200292.1
    • tryptophan synthase beta-subunit 1 (TSB1); FUNCTIONS IN: tryptophan synthase activity; INVOLVED IN: response to oxidative stress, tryptophan biosynthetic process, response to salt stress, indoleacetic acid biosynthetic process; LOCATED IN: chloroplast stroma, chloroplast; EXPRESSED IN: guard cell, root; CONTAINS InterPro DOMAIN/s: Tryptophan synthase, beta chain (InterPro:IPR006654), Tryptophan synthase, beta chain, conserved site (InterPro:IPR006653), Pyridoxal phosphate-dependent enzyme, beta subunit (InterPro:IPR001926); BEST Arabidopsis thaliana protein match is: tryptophan synthase beta-subunit 2 (TAIR:AT4G27070.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      22264594..22266902 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_124862.5 → NP_200292.1  tryptophan synthase beta-subunit 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_200292.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P14671
      UniProtKB/TrEMBL
      A0A178UE41, A0A654GB78, Q0WUI8
      Conserved Domains (1) summary
      PLN02618
      Location:64 → 470
      PLN02618; tryptophan synthase, beta chain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P14671.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
    Molecular Biology Databases
    Research Materials
    Tools