NTRA NADPH-dependent thioredoxin reductase A [Arabidopsis thaliana (thale cress)] - Gene

Summary

Official Symbol: NTRA
Official Full Name: NADPH-dependent thioredoxin reductase A
Primary source: TAIR:AT2G17420
Locus tag: AT2G17420
See related: Araport:AT2G17420
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: ATNTRA; F5J6.18; F5J6_18; NADPH-DEPENDENT THIOREDOXIN REDUCTASE 2; NADPH-dependent thioredoxin reductase A; NTR2; THIOREDOXIN REDUCTASE A
Summary: NADPH-dependent thioredoxin reductase, major cytosolic isoform
NEW: Try the new Gene table
Try the new Transcript table

Chromosome 2 - NC_003071.7 Genomic Context describing neighboring genes

Go to nucleotide: Graphics FASTA GenBank

GR1 and NTRA involved in pollen tube growth in the stigma of Arabidopsis.
Title: GR1 and NTRA involved in pollen tube growth in the stigma of Arabidopsis.
These data demonstrate that neither cytosolic nor mitochondrial NTRs are essential in plants.
Title: Inactivation of thioredoxin reductases reveals a complex interplay between thioredoxin and glutathione pathways in Arabidopsis development.

Submit: New GeneRIF Correction

NM_001335548.1

NM_127297.5

Function	Evidence Code	Pubs
enables thioredoxin-disulfide reductase (NADPH) activity	IDA Inferred from Direct Assay more info	PubMed
enables thioredoxin-disulfide reductase (NADPH) activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within cell redox homeostasis	IGI Inferred from Genetic Interaction more info	PubMed
acts_upstream_of_or_within pollen germination	IGI Inferred from Genetic Interaction more info	PubMed
involved_in pollen tube growth	IGI Inferred from Genetic Interaction more info	PubMed
acts_upstream_of_or_within positive regulation of cell division	IGI Inferred from Genetic Interaction more info	PubMed
involved_in removal of superoxide radicals	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within seed development	IGI Inferred from Genetic Interaction more info	PubMed

Component	Evidence Code	Pubs
located_in chloroplast	ISM Inferred from Sequence Model more info
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in cytosol	HDA more info	PubMed
located_in cytosol	IDA Inferred from Direct Assay more info	PubMed
located_in mitochondrial matrix	IDA Inferred from Direct Assay more info	PubMed
located_in mitochondrion	HDA more info	PubMed

NP_179334.5

NADPH-dependent thioredoxin reductase A (NTRA); FUNCTIONS IN: thioredoxin-disulfide reductase activity; INVOLVED IN: in 6 processes; LOCATED IN: cytosol, mitochondrial matrix; EXPRESSED IN: male gametophyte, guard cell, cultured cell, pollen tube, leaf; EXPRESSED DURING: L mature pollen stage, M germinated pollen stage, seedling growth, seed development stages; CONTAINS InterPro DOMAIN/s: Pyridine nucleotide-disulphide oxidoreductase, class-II, active site (InterPro:IPR008255), FAD-dependent pyridine nucleotide-disulphide oxidoreductase (InterPro:IPR013027), Pyridine nucleotide-disulphide oxidoreductase, class-II (InterPro:IPR000103), Pyridine nucleotide-disulphide oxidoreductase, NAD-binding region (InterPro:IPR001327), Thioredoxin reductase (InterPro:IPR005982); BEST Arabidopsis thaliana protein match is: NADPH-dependent thioredoxin reductase B (TAIR:AT4G35460.1); Has 20135 Blast hits to 20133 proteins in 2901 species: Archae - 588; Bacteria - 13597; Metazoa - 140; Fungi - 273; Plants - 163; Viruses - 0; Other Eukaryotes - 5374 (source: NCBI BLink).

NEW Try the new Transcript table

The following sections contain reference sequences that belong to a specific genome build. Explain