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    MMP matrix metalloproteinase [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 843353, updated on 18-Sep-2024

    Summary

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    Official Symbol
    MMP
    Official Full Name
    matrix metalloproteinase
    Primary source
    TAIR:AT1G70170
    Locus tag
    AT1G70170
    See related
    Araport:AT1G70170
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F20P5.11; F20P5_11; matrix metalloproteinase
    Summary
    mutant has Late flowering; Early senescence; Matrix Metalloproteinase
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    Genomic context

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    See MMP in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    1
    Sequence:
    Chromosome: 1; NC_003070.9 (26423874..26425356)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene zinc ion binding protein Neighboring gene zinc finger MYND domain protein Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene Sterile alpha motif (SAM) domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Mutation of the matrix metalloproteinase At2-MMP inhibits growth and causes late flowering and early senescence in Arabidopsis. Golldack D, et al. J Biol Chem, 2002 Feb 15. PMID 11726650
    2. Matrix metalloproteinases operate redundantly in Arabidopsis immunity against necrotrophic and biotrophic fungal pathogens. Zhao P, et al. PLoS One, 2017. PMID 28832648, Free PMC Article
    3. Family-wide characterization of matrix metalloproteinases from Arabidopsis thaliana reveals their distinct proteolytic activity and cleavage site specificity. Marino G, et al. Biochem J, 2014 Jan 15. PMID 24156403
    4. Identification of glycosylphosphatidylinositol-anchored proteins in Arabidopsis. A proteomic and genomic analysis. Borner GH, et al. Plant Physiol, 2003 Jun. PMID 12805588, Free PMC Article
    5. Prediction of glycosylphosphatidylinositol-anchored proteins in Arabidopsis. A genomic analysis. Borner GH, et al. Plant Physiol, 2002 Jun. PMID 12068095, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    NM_105685.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables metalloendopeptidase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables metallopeptidase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within defense response to fungus IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in developmental vegetative growth IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in negative regulation of leaf senescence IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of photoperiodism, flowering IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in response to cadmium ion IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in response to jasmonic acid IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in response to salt stress IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in apoplast IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in extracellular matrix IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in extracellular region ISM
    Inferred from Sequence Model
    more info
    		  
    located_in membrane TAS
    Traceable Author Statement
    more info
    		 PubMed 
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    matrix metalloproteinase
    NP_177174.1
    • matrix metalloproteinase (MMP); FUNCTIONS IN: metallopeptidase activity, metalloendopeptidase activity, zinc ion binding; INVOLVED IN: proteolysis, metabolic process; LOCATED IN: anchored to membrane; EXPRESSED IN: 7 plant structures; EXPRESSED DURING: L mature pollen stage, M germinated pollen stage, 4 anthesis, petal differentiation and expansion stage; CONTAINS InterPro DOMAIN/s: Peptidase M10, metallopeptidase (InterPro:IPR001818), Peptidoglycan binding-like (InterPro:IPR002477), Peptidase M10A, cysteine switch, zinc binding site (InterPro:IPR021158), Peptidase M10A, matrix metallopeptidase (InterPro:IPR021190), Peptidase, metallopeptidase (InterPro:IPR006026); BEST Arabidopsis thaliana protein match is: Matrixin family protein (TAIR:AT1G24140.1); Has 2679 Blast hits to 2485 proteins in 220 species: Archae - 2; Bacteria - 128; Metazoa - 2206; Fungi - 4; Plants - 185; Viruses - 44; Other Eukaryotes - 110 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      26423874..26425356
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_105685.4 → NP_177174.1  matrix metalloproteinase [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_177174.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O04529, Q0WVU1
      UniProtKB/TrEMBL
      A0A178WK53, A0A5S9WR94
      Conserved Domains (2) summary
      pfam00413
      Location:163 → 324
      Peptidase_M10; Matrixin
      pfam01471
      Location:62 → 115
      PG_binding_1; Putative peptidoglycan binding domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O04529.1

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