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    CAC3 acetyl Co-enzyme a carboxylase carboxyltransferase alpha subunit [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 818382, updated on 18-Sep-2024

    Summary

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    Official Symbol
    CAC3
    Official Full Name
    acetyl Co-enzyme a carboxylase carboxyltransferase alpha subunit
    Primary source
    TAIR:AT2G38040
    Locus tag
    AT2G38040
    See related
    Araport:AT2G38040
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    acetyl Co-enzyme a carboxylase carboxyltransferase alpha subunit; CARBOXYLTRANSFERASE ALPHA SUBUNIT; T8P21.5; T8P21_5
    Summary
    encodes the carboxyltransferase alpha subunit of acetyl-CoA carboxylase, involved in de novo fatty acid biosynthesis
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    Genomic context

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    See CAC3 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    12
    Sequence:
    Chromosome: 2; NC_003071.7 (15917032..15921170)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene Cysteine proteinases superfamily protein Neighboring gene tRNA-Glu Neighboring gene 3-oxo-5-alpha-steroid 4-dehydrogenase family protein Neighboring gene phosphate transporter 4;2 Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Proteomics of the chloroplast envelope membranes from Arabidopsis thaliana. Ferro M, et al. Mol Cell Proteomics, 2003 May. PMID 12766230
    2. Identification and dynamics of Arabidopsis adaptor protein-2 complex and its involvement in floral organ development. Yamaoka S, et al. Plant Cell, 2013 Aug. PMID 23975897, Free PMC Article
    3. Proteomic analysis of the 26S proteasome reveals its direct interaction with transit peptides of plastid protein precursors for their degradation. Sako K, et al. J Proteome Res, 2014 Jul 3. PMID 24846764
    4. The oligomeric stromal proteome of Arabidopsis thaliana chloroplasts. Peltier JB, et al. Mol Cell Proteomics, 2006 Jan. PMID 16207701
    5. Quantitative proteomics of a chloroplast SRP54 sorting mutant and its genetic interactions with CLPC1 in Arabidopsis. Rutschow H, et al. Plant Physiol, 2008 Sep. PMID 18633119, Free PMC Article

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_129360.4
    NM_179960.1

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables acetyl-CoA carboxylase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables acetyl-CoA carboxylase activity NAS
    Non-traceable Author Statement
    more info
    		  
    enables carboxyl- or carbamoyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in malonyl-CoA biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of acetyl-CoA carboxylase complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in chloroplast HDA PubMed 
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in chloroplast envelope HDA PubMed 
    located_in chloroplast stroma HDA PubMed 
    located_in endoplasmic reticulum HDA PubMed 
    located_in plastid HDA PubMed 

    General protein information

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    Preferred Names
    acetyl Co-enzyme a carboxylase carboxyltransferase alpha subunit
    NP_565880.1
    • acetyl Co-enzyme a carboxylase carboxyltransferase alpha subunit (CAC3); FUNCTIONS IN: acetyl-CoA carboxylase activity; INVOLVED IN: fatty acid biosynthetic process; LOCATED IN: acetyl-CoA carboxylase complex, chloroplast stroma, chloroplast, membrane, chloroplast envelope; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Acetyl-CoA carboxylase, alpha subunit, conserved region (InterPro:IPR020582), Acetyl-CoA carboxylase, alpha subunit (InterPro:IPR001095), Acetyl-coenzyme A carboxyltransferase, C-terminal (InterPro:IPR011763); Has 39620 Blast hits to 29201 proteins in 2891 species: Archae - 603; Bacteria - 9663; Metazoa - 14634; Fungi - 2688; Plants - 1525; Viruses - 82; Other Eukaryotes - 10425 (source: NCBI BLink).
    NP_850291.1
    • acetyl Co-enzyme a carboxylase carboxyltransferase alpha subunit (CAC3); FUNCTIONS IN: acetyl-CoA carboxylase activity; INVOLVED IN: fatty acid biosynthetic process; LOCATED IN: acetyl-CoA carboxylase complex, chloroplast, membrane, chloroplast envelope; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Acetyl-CoA carboxylase, alpha subunit, conserved region (InterPro:IPR020582), Acetyl-CoA carboxylase, alpha subunit (InterPro:IPR001095), Acetyl-coenzyme A carboxyltransferase, C-terminal (InterPro:IPR011763); Has 39620 Blast hits to 29201 proteins in 2891 species: Archae - 603; Bacteria - 9663; Metazoa - 14634; Fungi - 2688; Plants - 1525; Viruses - 82; Other Eukaryotes - 10425 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      15917032..15921170
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_129360.4 → NP_565880.1  acetyl Co-enzyme a carboxylase carboxyltransferase alpha subunit [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_565880.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q56YX0, Q9LD43
      UniProtKB/TrEMBL
      A0A178VYR6, A0A5S9X4Z8, A0A7G2EI77
      Conserved Domains (1) summary
      PLN03229
      Location:1 → 765
      PLN03229; acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional

    2. NM_179960.1 → NP_850291.1  acetyl Co-enzyme a carboxylase carboxyltransferase alpha subunit [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_850291.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q56YX0, Q9LD43
      UniProtKB/TrEMBL
      A0A178VYR6, A0A5S9X4Z8, A0A7G2EI77
      Conserved Domains (1) summary
      PLN03229
      Location:1 → 765
      PLN03229; acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LD43.1

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