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    Lexis1 lipid responsive LXR-induced inhibitor of cholesterol synthesis 1 [ Mus musculus (house mouse) ]

    Gene ID: 73941, updated on 29-Oct-2024

    Summary

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    Official Symbol
    Lexis1provided by MGI
    Official Full Name
    lipid responsive LXR-induced inhibitor of cholesterol synthesis 1provided by MGI
    Primary source
    MGI:MGI:1921191
    See related
    Ensembl:ENSMUSG00000087192 AllianceGenome:MGI:1921191
    Gene type
    ncRNA
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    LeXis; 4930412L05Rik
    Expression
    Low expression observed in reference dataset See more
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    Genomic context

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    See Lexis1 in Genome Data Viewer
    Location:
    4 B2; 4 28.58 cM
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (53205057..53217830, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (53204930..53218681, complement)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene ATP-binding cassette, sub-family A member 1 Neighboring gene predicted gene, 54225 Neighboring gene RIKEN cDNA 4930522O17 gene Neighboring gene predicted gene, 57725

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. A PPARγ/long noncoding RNA axis regulates adipose thermoneutral remodeling in mice. Zhang Z, et al. J Clin Invest, 2023 Nov 1. PMID 37909330, Free PMC Article
    2. Feedback modulation of cholesterol metabolism by the lipid-responsive non-coding RNA LeXis. Sallam T, et al. Nature, 2016 Jun 2. PMID 27251289, Free PMC Article
    3. USP7 represses lineage differentiation genes in mouse embryonic stem cells by both catalytic and noncatalytic activities. Liu C, et al. Sci Adv, 2023 May 19. PMID 37196079, Free PMC Article
    4. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
    5. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_190075.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL833806
      Related
      ENSMUST00000298552.1

    2. NR_190076.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL833806

    3. NR_190077.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL833806

    4. NR_190078.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL833806

    5. NR_190079.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL833806

    6. NR_190080.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL833806

    7. NR_190081.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL833806

    8. NR_190082.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL833806

    9. NR_190083.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL833806

    10. NR_190084.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL833806

    11. NR_190085.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL833806

    12. NR_190086.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL833806
      Related
      ENSMUST00000146501.8

    13. NR_190087.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL833806

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      53205057..53217830 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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