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    Fam168a family with sequence similarity 168, member A [ Rattus norvegicus (Norway rat) ]

    Gene ID: 361614, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Fam168aprovided by RGD
    Official Full Name
    family with sequence similarity 168, member Aprovided by RGD
    Primary source
    RGD:1308929
    See related
    EnsemblRapid:ENSRNOG00000018873 AllianceGenome:RGD:1308929
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1308929
    Summary
    Predicted to be involved in positive regulation of base-excision repair. Orthologous to human FAM168A (family with sequence similarity 168 member A). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Brain (RPKM 214.3), Adrenal (RPKM 85.1) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Fam168a in Genome Data Viewer
    Location:
    1q32
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (164469447..164615542)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (155057352..155203439)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (165723278..165880612)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA SNORA4 Neighboring gene RAB6A, member RAS oncogene family Neighboring gene pleckstrin homology domain containing B1 Neighboring gene RELT, TNF receptor Neighboring gene Rho guanine nucleotide exchange factor 17 Neighboring gene microRNA 3102

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. TCRP1 contributes to cisplatin resistance by preventing Pol β degradation in lung cancer cells. Liu X, et al. Mol Cell Biochem, 2015 Jan. PMID 25260657
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in positive regulation of base-excision repair IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in positive regulation of base-excision repair ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    protein FAM168A

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001108494.1 → NP_001101964.1  protein FAM168A

      See identical proteins and their annotated locations for NP_001101964.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473956
      UniProtKB/TrEMBL
      A0A8I5ZR57, A6I6R4, D3ZHW1
      Conserved Domains (1) summary
      pfam14944
      Location:1 → 244
      TCRP1; Tongue Cancer Chemotherapy Resistant Protein 1

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      164469447..164615542
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006229773.5 → XP_006229835.1  protein FAM168A isoform X4

      See identical proteins and their annotated locations for XP_006229835.1

      UniProtKB/TrEMBL
      A0A8I5ZR57, A6I6R5
      Related
      ENSRNOP00000081214.2, ENSRNOT00000097710.2
      Conserved Domains (1) summary
      pfam14944
      Location:1 → 235
      TCRP1; Tongue Cancer Chemotherapy Resistant Protein 1

    2. XM_039082504.2 → XP_038938432.1  protein FAM168A isoform X3

      UniProtKB/TrEMBL
      A0A8I5ZR57, A6I6R4, D3ZHW1
      Related
      ENSRNOP00000087972.1, ENSRNOT00000106607.2
      Conserved Domains (1) summary
      pfam14944
      Location:1 → 244
      TCRP1; Tongue Cancer Chemotherapy Resistant Protein 1

    3. XM_039082510.2 → XP_038938438.1  protein FAM168A isoform X4

      UniProtKB/TrEMBL
      A0A8I5ZR57, A6I6R5
      Conserved Domains (1) summary
      pfam14944
      Location:1 → 235
      TCRP1; Tongue Cancer Chemotherapy Resistant Protein 1

    4. XM_017589376.3 → XP_017444865.1  protein FAM168A isoform X1

      UniProtKB/TrEMBL
      A0A8I5ZR57
      Related
      ENSRNOP00000109680.1, ENSRNOT00000164813.1
      Conserved Domains (1) summary
      pfam14944
      Location:12 → 255
      TCRP1; Tongue Cancer Chemotherapy Resistant Protein 1

    5. XM_039082512.2 → XP_038938440.1  protein FAM168A isoform X5

      Conserved Domains (1) summary
      pfam14944
      Location:12 → 204
      TCRP1; Tongue Cancer Chemotherapy Resistant Protein 1

    6. XM_017589377.3 → XP_017444866.1  protein FAM168A isoform X2

      UniProtKB/TrEMBL
      A0A8I5ZR57
      Related
      ENSRNOP00000025827.6, ENSRNOT00000025827.7
      Conserved Domains (1) summary
      pfam14944
      Location:12 → 246
      TCRP1; Tongue Cancer Chemotherapy Resistant Protein 1
    Nucleotide Protein Strain
    Heading Accession and Version

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