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    Znf865 zinc finger protein 865 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 100911196, updated on 27-Dec-2024

    Summary

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    Official Symbol
    Znf865provided by RGD
    Official Full Name
    zinc finger protein 865provided by RGD
    Primary source
    RGD:6494165
    See related
    EnsemblRapid:ENSRNOG00000028628 AllianceGenome:RGD:6494165
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Orthologous to human ZNF865 (zinc finger protein 865). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Lung (RPKM 36.4), Thymus (RPKM 35.5) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Znf865 in Genome Data Viewer
    Location:
    1q12
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (77839504..77853507, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (68810664..68824652, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (72362242..72374599, complement)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene U6 spliceosomal RNA Neighboring gene zinc finger protein 865 Neighboring gene zinc finger protein 524 Neighboring gene FLT3-interacting zinc finger 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    zinc finger protein 865

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001401756.1 → NP_001388685.1  zinc finger protein 865

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000001
      UniProtKB/TrEMBL
      A0A8I5ZTV8
      Related
      ENSRNOP00000104766.1, ENSRNOT00000172652.1

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      77839504..77853507 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063284309.1 → XP_063140379.1  zinc finger protein 865 isoform X5

    2. XM_039100562.2 → XP_038956490.1  zinc finger protein 865 isoform X2

      Conserved Domains (5) summary
      PHA03378
      Location:142 → 328
      PHA03378; EBNA-3B; Provisional
      COG5048
      Location:328 → 400
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:527 → 547
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:420 → 440
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:540 → 563
      zf-H2C2_2; Zinc-finger double domain

    3. XM_063284300.1 → XP_063140370.1  zinc finger protein 865 isoform X4

      UniProtKB/TrEMBL
      A6KNR3, M0R740

    4. XM_017589961.3 → XP_017445450.1  zinc finger protein 865 isoform X1

      UniProtKB/TrEMBL
      A0A8I5ZTV8
      Related
      ENSRNOP00000101500.1, ENSRNOT00000155383.1
      Conserved Domains (5) summary
      PHA03378
      Location:163 → 349
      PHA03378; EBNA-3B; Provisional
      COG5048
      Location:349 → 421
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:548 → 568
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:441 → 461
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:561 → 584
      zf-H2C2_2; Zinc-finger double domain

    5. XM_008759010.3 → XP_008757232.1  zinc finger protein 865 isoform X3

      See identical proteins and their annotated locations for XP_008757232.1

      Conserved Domains (6) summary
      COG5048
      Location:381 → 453
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:580 → 600
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:473 → 493
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:252 → 274
      zf-C2H2; Zinc finger, C2H2 type
      pfam12446
      Location:304 → 380
      DUF3682; Protein of unknown function (DUF3682)
      pfam13465
      Location:593 → 615
      zf-H2C2_2; Zinc-finger double domain

    RNA

    1. XR_350148.3 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

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