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    Ints14 integrator complex subunit 14 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 300782, updated on 27-Dec-2024

    Summary

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    Official Symbol
    Ints14provided by RGD
    Official Full Name
    integrator complex subunit 14provided by RGD
    Primary source
    RGD:1359616
    See related
    EnsemblRapid:ENSRNOG00000012469 AllianceGenome:RGD:1359616
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Vwa9; RGD1359616
    Summary
    Predicted to be involved in snRNA 3'-end processing. Predicted to be located in cytoplasm. Predicted to be part of integrator complex. Predicted to be active in nucleus. Orthologous to human INTS14 (integrator complex subunit 14). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Thymus (RPKM 118.3), Kidney (RPKM 103.0) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Ints14 in Genome Data Viewer
    Location:
    8q24
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (74370687..74398153)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (65475788..65500807)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (70446157..70471140)

    Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene DENN domain containing 4A Neighboring gene small nucleolar RNA SNORA17 Neighboring gene solute carrier family 24 member 1 Neighboring gene 3-hydroxyacyl-CoA dehydratase 3 Neighboring gene ATP synthase membrane subunit DAPIT, mitochondrial-like Neighboring gene dipeptidylpeptidase 8

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Clone Names

    • MGC94254

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in snRNA 3'-end processing IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    part_of integrator complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of integrator complex ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in nucleus ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    integrator complex subunit 14
    Names
    UPF0464 protein C15orf44 homolog
    von Willebrand factor A domain containing 9
    von Willebrand factor A domain-containing protein 9

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001007663.1 → NP_001007664.1  integrator complex subunit 14

      See identical proteins and their annotated locations for NP_001007664.1

      Status: PROVISIONAL

      Source sequence(s)
      BC082006
      UniProtKB/Swiss-Prot
      Q66H58
      UniProtKB/TrEMBL
      A0A8I6G784
      Conserved Domains (2) summary
      pfam13519
      Location:3 → 114
      VWA_2; von Willebrand factor type A domain
      cl17190
      Location:365 → 489
      NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086026.1 Reference GRCr8

      Range
      74370687..74398153
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_008766239.4 → XP_008764461.1  integrator complex subunit 14 isoform X1

      See identical proteins and their annotated locations for XP_008764461.1

      UniProtKB/Swiss-Prot
      Q66H58
      UniProtKB/TrEMBL
      A0A8I6G784
      Related
      ENSRNOP00000016798.7, ENSRNOT00000016798.9
      Conserved Domains (2) summary
      pfam13519
      Location:3 → 114
      VWA_2; von Willebrand factor type A domain
      cl17190
      Location:365 → 489
      NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q66H58.1 GenPept UniProtKB/Swiss-Prot:Q66H58

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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