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    AICARFT/IMPCHase bienzyme family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 818069, updated on 18-Sep-2024

    Summary

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    Official Full Name
    AICARFT/IMPCHase bienzyme family protein
    Primary source
    TAIR:AT2G35040
    Locus tag
    AT2G35040
    See related
    Araport:AT2G35040
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F19I3.27; F19I3_27
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    Genomic context

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    Location:
    chromosome: 2
    Exon count:
    12
    Sequence:
    Chromosome: 2; NC_003071.7 (14765145..14768329, complement)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene Pentatricopeptide repeat (PPR) superfamily protein Neighboring gene urease accessory protein D Neighboring gene kinase superfamily with octicosapeptide/Phox/Bem1p domain-containing protein Neighboring gene K+ uptake permease 11

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The chloroplast lumen and stromal proteomes of Arabidopsis thaliana show differential sensitivity to short- and long-term exposure to low temperature. Goulas E, et al. Plant J, 2006 Sep. PMID 16923014
    2. The oligomeric stromal proteome of Arabidopsis thaliana chloroplasts. Peltier JB, et al. Mol Cell Proteomics, 2006 Jan. PMID 16207701
    3. Identification and characterization of nuclear pore complex components in Arabidopsis thaliana. Tamura K, et al. Plant Cell, 2010 Dec. PMID 21189294, Free PMC Article
    4. AT_CHLORO, a comprehensive chloroplast proteome database with subplastidial localization and curated information on envelope proteins. Ferro M, et al. Mol Cell Proteomics, 2010 Jun. PMID 20061580, Free PMC Article
    5. Advanced proteomic analyses yield a deep catalog of ubiquitylation targets in Arabidopsis. Kim DY, et al. Plant Cell, 2013 May. PMID 23667124, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001202752.1
    NM_179909.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables IMP cyclohydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables phosphoribosylaminoimidazolecarboxamide formyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in 'de novo' IMP biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within response to cold IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast HDA PubMed 
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in chloroplast stroma HDA PubMed 
    located_in plastid HDA PubMed 
    located_in stromule IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    AICARFT/IMPCHase bienzyme family protein
    NP_001189681.1
    • AICARFT/IMPCHase bienzyme family protein; FUNCTIONS IN: phosphoribosylaminoimidazolecarboxamide formyltransferase activity, IMP cyclohydrolase activity, catalytic activity; INVOLVED IN: response to cold, purine nucleotide biosynthetic process; LOCATED IN: stromule; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: AICARFT/IMPCHase bienzyme, transformylase domain (InterPro:IPR013982), AICARFT/IMPCHase bienzyme (InterPro:IPR002695), MGS-like (InterPro:IPR011607).
    NP_850240.1
    • AICARFT/IMPCHase bienzyme family protein; FUNCTIONS IN: phosphoribosylaminoimidazolecarboxamide formyltransferase activity, IMP cyclohydrolase activity, catalytic activity; INVOLVED IN: response to cold, purine nucleotide biosynthetic process; LOCATED IN: stromule, chloroplast, chloroplast stroma; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: AICARFT/IMPCHase bienzyme, transformylase domain (InterPro:IPR013982), AICARFT/IMPCHase bienzyme (InterPro:IPR002695), MGS-like (InterPro:IPR011607); Has 10802 Blast hits to 10325 proteins in 2522 species: Archae - 69; Bacteria - 5512; Metazoa - 346; Fungi - 183; Plants - 62; Viruses - 6; Other Eukaryotes - 4624 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      14765145..14768329 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_179909.2 → NP_850240.1  AICARFT/IMPCHase bienzyme family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_850240.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VXL4, A0A5S9X4B6, Q8RWT5
      Conserved Domains (1) summary
      PLN02891
      Location:52 → 596
      PLN02891; IMP cyclohydrolase

    2. NM_001202752.1 → NP_001189681.1  AICARFT/IMPCHase bienzyme family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001189681.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VXL4, O64767
      Conserved Domains (3) summary
      PLN02891
      Location:1 → 545
      PLN02891; IMP cyclohydrolase
      cd01421
      Location:21 → 208
      IMPCH; Inosine monophosphate cyclohydrolase domain. This is the N-terminal domain in the purine biosynthesis pathway protein ATIC (purH). The bifunctional ATIC protein contains a C-terminal ATIC formylase domain that formylates ...
      pfam01808
      Location:154 → 474
      AICARFT_IMPCHas; AICARFT/IMPCHase bienzyme
    Nucleotide Protein
    Heading Accession and Version

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