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    GGPS2 geranylgeranyl pyrophosphate synthase 2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 816912, updated on 18-Sep-2024

    Summary

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    Official Symbol
    GGPS2
    Official Full Name
    geranylgeranyl pyrophosphate synthase 2
    Primary source
    TAIR:AT2G23800
    Locus tag
    AT2G23800
    See related
    Araport:AT2G23800
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F27L4.2; F27L4_2; geranylgeranyl pyrophosphate synthase 2; GERANYLGERANYL PYROPHOSPHATE SYNTHASE 5; GGPS5; PREGERANYLGERANYL PYROPHOSPHATE SYNTHASE
    Summary
    encodes an endoplasmic reticulum-targeted geranylgeranyl pyrophosphate synthase
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    Genomic context

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    See GGPS2 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    1
    Sequence:
    Chromosome: 2; NC_003071.7 (10131485..10132779, complement)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene RING/U-box superfamily protein Neighboring gene calcium uniporter (DUF607) Neighboring gene miscRNA Neighboring gene tetraspanin8

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Cloning and functional expression of a novel geranylgeranyl pyrophosphate synthase gene from Arabidopsis thaliana in Escherichia coli. Zhu XF, et al. Plant Cell Physiol, 1997 Mar. PMID 9150607
    2. Five geranylgeranyl diphosphate synthases expressed in different organs are localized into three subcellular compartments in Arabidopsis. Okada K, et al. Plant Physiol, 2000 Apr. PMID 10759500, Free PMC Article
    3. Characterization of the GGPP synthase gene family in Arabidopsis thaliana. Beck G, et al. Plant Mol Biol, 2013 Jul. PMID 23729351
    4. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    NM_127943.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables dimethylallyltranstransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables farnesyltranstransferase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables farnesyltranstransferase activity IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    enables geranyltranstransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in farnesyl diphosphate biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in geranyl diphosphate biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in geranylgeranyl diphosphate biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within isoprenoid biosynthetic process TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in endoplasmic reticulum IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    geranylgeranyl pyrophosphate synthase 2
    NP_179960.1
    • geranylgeranyl pyrophosphate synthase 2 (GGPS2); CONTAINS InterPro DOMAIN/s: Terpenoid synthase (InterPro:IPR008949), Polyprenyl synthetase-related (InterPro:IPR017446), Polyprenyl synthetase (InterPro:IPR000092); BEST Arabidopsis thaliana protein match is: geranylgeranyl pyrophosphate synthase 4 (TAIR:AT2G18640.1); Has 16682 Blast hits to 16674 proteins in 2948 species: Archae - 341; Bacteria - 9381; Metazoa - 343; Fungi - 516; Plants - 473; Viruses - 12; Other Eukaryotes - 5616 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      10131485..10132779 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_127943.3 → NP_179960.1  geranylgeranyl pyrophosphate synthase 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_179960.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O04046, Q38917, Q7DN59
      UniProtKB/TrEMBL
      A0A178VTY2, A0A384LH49, A0A654EWZ9, B6DVJ8
      Conserved Domains (1) summary
      cd00685
      Location:112 → 374
      Trans_IPPS_HT; Trans-Isoprenyl Diphosphate Synthases, head-to-tail
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O04046.2

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