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    SKdZeta SHAGGY-related protein kinase dZeta [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 817649, updated on 18-Sep-2024

    Summary

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    Official Symbol
    SKdZeta
    Official Full Name
    SHAGGY-related protein kinase dZeta
    Primary source
    TAIR:AT2G30980
    Locus tag
    AT2G30980
    See related
    Araport:AT2G30980
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    A. THALIANA SHAGGY-LIKE KINASE GROUP 2 2; ASKdZeta; ATSK2-2; ATSK23; BIL1; BIN2-LIKE 1; F7F1.19; F7F1_19; SHAGGY-LIKE PROTEIN KINASE 23; SHAGGY-related protein kinase dZeta
    Summary
    Encodes a GSK3-like protein kinase. This protein can interact with the BZR1 protein involved in brassinosteroid-mediated signaling in a Y2H assay and promotes BZR1 phosphorylation in protoplasts.
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    Genomic context

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    See SKdZeta in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    12
    Sequence:
    Chromosome: 2; NC_003071.7 (13182025..13185973, complement)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene FtsH extracellular protease family Neighboring gene ncRNA Neighboring gene myosin-M heavy chain-like protein Neighboring gene ncRNA Neighboring gene aspartate aminotransferase 1 Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene arginine N-methyltransferase, putative (DUF688)

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. BIL1-mediated MP phosphorylation integrates PXY and cytokinin signalling in secondary growth. Han S, et al. Nat Plants, 2018 Aug. PMID 29988154
    2. Brassinosteroids regulate pavement cell growth by mediating BIN2-induced microtubule stabilization. Liu X, et al. J Exp Bot, 2018 Feb 23. PMID 29329424, Free PMC Article
    3. BIN2 functions redundantly with other Arabidopsis GSK3-like kinases to regulate brassinosteroid signaling. Yan Z, et al. Plant Physiol, 2009 Jun. PMID 19395409, Free PMC Article
    4. BRASSINOSTEROID INSENSITIVE2 interacts with ABSCISIC ACID INSENSITIVE5 to mediate the antagonism of brassinosteroids to abscisic acid during seed germination in Arabidopsis. Hu Y, et al. Plant Cell, 2014 Nov. PMID 25415975, Free PMC Article
    5. Nucleocytoplasmic shuttling of BZR1 mediated by phosphorylation is essential in Arabidopsis brassinosteroid signaling. Ryu H, et al. Plant Cell, 2007 Sep. PMID 17873094, Free PMC Article

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. In vitro and in vivo pull-down assays confirmed that BIN2 interacts with tubulin proteins. High-speed co-sedimentation assays demonstrated that BIN2 also binds microtubules. The Arabidopsis genome also encodes two BIN2 homologs, BIN2-LIKE 1 (BIL1) and BIL2, which function redundantly with BIN2.
      Title: Brassinosteroids regulate pavement cell growth by mediating BIN2-induced microtubule stabilization.
    2. BIN2-LIKE 1 (BIL1), a glycogen synthase kinase 3, integrates the PHLOEM INTERCALATED WITH XYLEM/tracheary element differentiation inhibitory factor (TDIF) RECEPTOR (PXY/TDR) module into MONOPTEROS/AUXIN RESPONSE FACTOR 5 (MP/ARF5) transcription factor action during secondary growth.
      Title: BIL1-mediated MP phosphorylation integrates PXY and cytokinin signalling in secondary growth.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    NM_128652.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within brassinosteroid mediated signaling pathway IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within protein phosphorylation IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of protein localization IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of root meristem growth IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within response to light stimulus IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within response to water deprivation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    SHAGGY-related protein kinase dZeta
    NP_180655.1
    • SHAGGY-related protein kinase dZeta (SKdZeta); FUNCTIONS IN: protein serine/threonine kinase activity, protein kinase activity, kinase activity, ATP binding; INVOLVED IN: brassinosteroid mediated signaling pathway, protein amino acid phosphorylation, regulation of protein localization; LOCATED IN: cellular_component unknown; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), Protein kinase, catalytic domain (InterPro:IPR000719), Serine/threonine-protein kinase domain (InterPro:IPR002290), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271); BEST Arabidopsis thaliana protein match is: GSK3/SHAGGY-like protein kinase 1 (TAIR:AT1G06390.2); Has 110013 Blast hits to 108778 proteins in 3905 species: Archae - 83; Bacteria - 10808; Metazoa - 40209; Fungi - 11817; Plants - 28363; Viruses - 415; Other Eukaryotes - 18318 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      13182025..13185973 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_128652.4 → NP_180655.1  SHAGGY-related protein kinase dZeta [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_180655.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O80862, Q39010, Q541C5, Q8LAX6
      UniProtKB/TrEMBL
      A0A178W1X9, A0A5S9X2R0, A0A7G2EDG8
      Conserved Domains (1) summary
      cd14137
      Location:67 → 359
      STKc_GSK3; The catalytic domain of the Serine/Threonine Kinase, Glycogen Synthase Kinase 3
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q39010.2

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