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    ABCB6 P-glycoprotein 6 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 818533, updated on 18-Sep-2024

    Summary

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    Official Symbol
    ABCB6
    Official Full Name
    P-glycoprotein 6
    Primary source
    TAIR:AT2G39480
    Locus tag
    AT2G39480
    See related
    Araport:AT2G39480
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATP-binding cassette B6; F12L6.14; F12L6_14; P-glycoprotein 6; PGP6
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    Genomic context

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    See ABCB6 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    12
    Sequence:
    Chromosome: 2; NC_003071.7 (16477792..16485039, complement)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene Cation efflux family protein Neighboring gene ribosomal protein L23AA Neighboring gene PsbP-like protein 2 Neighboring gene ncRNA Neighboring gene F-box family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A transportome-scale amiRNA-based screen identifies redundant roles of Arabidopsis ABCB6 and ABCB20 in auxin transport. Zhang Y, et al. Nat Commun, 2018 Oct 11. PMID 30310073, Free PMC Article
    2. Mapping the Arabidopsis organelle proteome. Dunkley TP, et al. Proc Natl Acad Sci U S A, 2006 Apr 25. PMID 16618929, Free PMC Article
    3. Mapping the signaling network of BIN2 kinase using TurboID-mediated biotin labeling and phosphoproteomics. Kim TW, et al. Plant Cell, 2023 Mar 15. PMID 36660928, Free PMC Article
    4. Arabidopsis plasmodesmal proteome. Fernandez-Calvino L, et al. PLoS One, 2011 Apr 20. PMID 21533090, Free PMC Article
    5. Putative glycosyltransferases and other plant Golgi apparatus proteins are revealed by LOPIT proteomics. Nikolovski N, et al. Plant Physiol, 2012 Oct. PMID 22923678, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. a strong redundant role for the unstudied ABCB6 and ABCB20 genes in auxin transport and response, is reported.
      Title: A transportome-scale amiRNA-based screen identifies redundant roles of Arabidopsis ABCB6 and ABCB20 in auxin transport.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001336781.1
    NM_129506.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables ABC-type transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATPase-coupled transmembrane transporter activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in Golgi apparatus HDA PubMed 
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in plasma membrane HDA PubMed 
    located_in plasmodesma HDA PubMed 

    General protein information

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    Preferred Names
    P-glycoprotein 6
    NP_181480.1
    • P-glycoprotein 6 (PGP6); FUNCTIONS IN: ATPase activity, coupled to transmembrane movement of substances; INVOLVED IN: transport, transmembrane transport; LOCATED IN: nucleus, plasma membrane; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: ATPase, AAA+ type, core (InterPro:IPR003593), ABC transporter-like (InterPro:IPR003439), ABC transporter, transmembrane domain, type 1 (InterPro:IPR011527), ABC transporter integral membrane type 1 (InterPro:IPR017940), ABC transporter, transmembrane domain (InterPro:IPR001140); BEST Arabidopsis thaliana protein match is: P-glycoprotein 20 (TAIR:AT3G55320.1); Has 727628 Blast hits to 364161 proteins in 4096 species: Archae - 12661; Bacteria - 576901; Metazoa - 18207; Fungi - 12101; Plants - 9039; Viruses - 13; Other Eukaryotes - 98706 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      16477792..16485039 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_129506.2 → NP_181480.1  P-glycoprotein 6 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_181480.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O80635, Q8LPT1
      UniProtKB/TrEMBL
      A0A654F1L5
      Conserved Domains (3) summary
      PTZ00265
      Location:69 → 1389
      PTZ00265; multidrug resistance protein (mdr1); Provisional
      pfam00664
      Location:91 → 364
      ABC_membrane; ABC transporter transmembrane region
      cl21455
      Location:412 → 646
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

    2. NM_001336781.1 → NP_001324134.1  P-glycoprotein 6 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VUH1, A0A1P8AZ84
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8LPT1.2

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