Lrrc78 leucine rich repeat containing 78 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Lrrc78provided by MGI
Official Full Name: leucine rich repeat containing 78provided by MGI
Primary source: MGI:MGI:5579435
See related: Ensembl:ENSMUSG00000099564 AllianceGenome:MGI:5579435
Gene type: protein coding
RefSeq status: PREDICTED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Gm28729
Summary: Predicted to enable ribonuclease inhibitor activity. Predicted to be involved in cell migration; regulation of Arp2/3 complex-mediated actin nucleation; and regulation of angiogenesis. Predicted to be part of angiogenin-PRI complex. Predicted to be active in lamellipodium; nucleoplasm; and plasma membrane. Orthologous to human LRRC78P (leucine rich repeat containing 78, pseudogene). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in bladder adult (RPKM 6.0), testis adult (RPKM 2.1) and 5 other tissues See more
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Genomic context

Location:: 9 E3.3; 9

Exon count:: 13

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	9	NC_000075.7 (96368040..96407643, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	9	NC_000075.6 (96485987..96525852, complement)

Chromosome 9 - NC_000075.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (1)

General gene information

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Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables ribonuclease inhibitor activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in cell migration	IBA Inferred from Biological aspect of Ancestor more info
involved_in regulation of Arp2/3 complex-mediated actin nucleation	IBA Inferred from Biological aspect of Ancestor more info
involved_in regulation of angiogenesis	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
part_of angiogenin-PRI complex	IBA Inferred from Biological aspect of Ancestor more info
is_active_in lamellipodium	IBA Inferred from Biological aspect of Ancestor more info
is_active_in nucleoplasm	IBA Inferred from Biological aspect of Ancestor more info
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: uncharacterized protein LOC102635744

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.