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    Grpel2 GrpE-like 2, mitochondrial [ Mus musculus (house mouse) ]

    Gene ID: 17714, updated on 9-Dec-2024

    Summary

    Official Symbol
    Grpel2provided by MGI
    Official Full Name
    GrpE-like 2, mitochondrialprovided by MGI
    Primary source
    MGI:MGI:1334416
    See related
    Ensembl:ENSMUSG00000024580 AllianceGenome:MGI:1334416
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    mt-GrpE#2; mt-Grpel2
    Summary
    Enables unfolded protein binding activity. Predicted to be involved in protein import into mitochondrial matrix. Located in mitochondrial inner membrane. Orthologous to human GRPEL2 (GrpE like 2, mitochondrial). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in CNS E18 (RPKM 8.8), CNS E14 (RPKM 7.8) and 28 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Grpel2 in Genome Data Viewer
    Location:
    18 E1; 18 34.69 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 18 NC_000084.7 (61845495..61860068, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 18 NC_000084.6 (61712424..61726358, complement)

    Chromosome 18 - NC_000084.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer mm9_chr18:61857809-61858110 Neighboring gene STARR-seq mESC enhancer starr_44762 Neighboring gene predicted gene, 38165 Neighboring gene interleukin 17B Neighboring gene prenylcysteine oxidase 1 like Neighboring gene RIKEN cDNA 1500015A07 gene Neighboring gene STARR-positive B cell enhancer ABC_E8720 Neighboring gene predicted gene, 17883 Neighboring gene STARR-positive B cell enhancer ABC_E7594 Neighboring gene actin filament associated protein 1-like 1 Neighboring gene predicted gene, 41748 Neighboring gene predicted gene, 35919 Neighboring gene actin binding LIM protein family, member 3

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 
    • Targeted (1) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General protein information

    Preferred Names
    grpE protein homolog 2, mitochondrial

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_021296.2NP_067271.1  grpE protein homolog 2, mitochondrial precursor

      See identical proteins and their annotated locations for NP_067271.1

      Status: VALIDATED

      Source sequence(s)
      AK145493, BC094583, BY249944
      Consensus CDS
      CCDS29288.1
      UniProtKB/Swiss-Prot
      O88396, Q3ULH8, Q9CQ97
      UniProtKB/TrEMBL
      Q0VB85, Q3UYQ9
      Related
      ENSMUSP00000053440.8, ENSMUST00000062991.9
      Conserved Domains (1) summary
      cd00446
      Location:73216
      GrpE; nucleotide exchange factor GrpE

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000084.7 Reference GRCm39 C57BL/6J

      Range
      61845495..61860068 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    RNA

    1. XR_385980.5 RNA Sequence