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    CPSF73-I cleavage and polyadenylation specificity factor 73-I [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 842393, updated on 18-Sep-2024

    Summary

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    Official Symbol
    CPSF73-I
    Official Full Name
    cleavage and polyadenylation specificity factor 73-I
    Primary source
    TAIR:AT1G61010
    Locus tag
    AT1G61010
    See related
    Araport:AT1G61010
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    cleavage and polyadenylation specificity factor 73-I; T7P1.15; T7P1_15
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    Genomic context

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    See CPSF73-I in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    7
    Sequence:
    Chromosome: 1; NC_003070.9 (22474267..22477765, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene Glycine cleavage T-protein family Neighboring gene SCR-like 7 Neighboring gene S3 self-incompatibility locus-linked pollen protein Neighboring gene kinetochore protein Neighboring gene tRNA-Arg Neighboring gene WAPL (Wings apart-like protein regulation of heterochromatin) protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. snRNA 3' End Processing by a CPSF73-Containing Complex Essential for Development in Arabidopsis. Liu Y, et al. PLoS Biol, 2016 Oct. PMID 27780203, Free PMC Article
    2. Distinctive interactions of the Arabidopsis homolog of the 30 kD subunit of the cleavage and polyadenylation specificity factor (AtCPSF30) with other polyadenylation factor subunits. Rao S, et al. BMC Cell Biol, 2009 Jul 2. PMID 19573236, Free PMC Article
    3. The 73 kD subunit of the cleavage and polyadenylation specificity factor (CPSF) complex affects reproductive development in Arabidopsis. Xu R, et al. Plant Mol Biol, 2006 Jul. PMID 16897494
    4. Defective RNA processing enhances RNA silencing and influences flowering of Arabidopsis. Herr AJ, et al. Proc Natl Acad Sci U S A, 2006 Oct 10. PMID 17008405, Free PMC Article
    5. Unique features of plant cleavage and polyadenylation specificity factor revealed by proteomic studies. Zhao H, et al. Plant Physiol, 2009 Nov. PMID 19748916, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Two 73 kD subunits of the AtCPSF complex appear to have special functions during flower development.[CPSF73-I]
      Title: The 73 kD subunit of the cleavage and polyadenylation specificity factor (CPSF) complex affects reproductive development in Arabidopsis.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001036138.2
    NM_001333924.1
    NM_001333925.1
    NM_104782.4
    NM_179504.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within snRNA processing IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    cleavage and polyadenylation specificity factor 73-I
    NP_001031215.1
    • cleavage and polyadenylation specificity factor 73-I (CPSF73-I); CONTAINS InterPro DOMAIN/s: Beta-Casp domain (InterPro:IPR022712), RNA-metabolising metallo-beta-lactamase (InterPro:IPR011108), Beta-lactamase-like (InterPro:IPR001279), Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term (InterPro:IPR021718); BEST Arabidopsis thaliana protein match is: cleavage and polyadenylation specificity factor 73 kDa subunit-II (TAIR:AT2G01730.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).
    NP_001319278.1
    • cleavage and polyadenylation specificity factor 73-I (CPSF73-I); CONTAINS InterPro DOMAIN/s: Beta-Casp domain (InterPro:IPR022712), RNA-metabolising metallo-beta-lactamase (InterPro:IPR011108), Beta-lactamase-like (InterPro:IPR001279), Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term (InterPro:IPR021718); BEST Arabidopsis thaliana protein match is: cleavage and polyadenylation specificity factor 73 kDa subunit-II (TAIR:AT2G01730.1); Has 5076 Blast hits to 5016 proteins in 1410 species: Archae - 467; Bacteria - 2637; Metazoa - 590; Fungi - 276; Plants - 187; Viruses - 2; Other Eukaryotes - 917 (source: NCBI BLink).
    NP_849835.1
    • cleavage and polyadenylation specificity factor 73-I (CPSF73-I); CONTAINS InterPro DOMAIN/s: Beta-Casp domain (InterPro:IPR022712), RNA-metabolising metallo-beta-lactamase (InterPro:IPR011108), Beta-lactamase-like (InterPro:IPR001279), Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term (InterPro:IPR021718); BEST Arabidopsis thaliana protein match is: cleavage and polyadenylation specificity factor 73 kDa subunit-II (TAIR:AT2G01730.1); Has 5076 Blast hits to 5016 proteins in 1410 species: Archae - 467; Bacteria - 2637; Metazoa - 590; Fungi - 276; Plants - 187; Viruses - 2; Other Eukaryotes - 917 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      22474267..22477765 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001036138.2 → NP_001031215.1  cleavage and polyadenylation specificity factor 73-I [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001031215.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8VY18, Q9C952
      UniProtKB/TrEMBL
      A0A178WGJ2, A0A5S9WN75, A0A7G2E2C2
      Conserved Domains (3) summary
      COG1236
      Location:24 → 462
      YSH1; RNA processing exonuclease, beta-lactamase fold, Cft2 family [Translation, ribosomal structure and biogenesis]
      cd16292
      Location:22 → 215
      CPSF3-like_MBL-fold; cleavage and polyadenylation specificity factor (CPSF) subunit 3 and related proteins; MBL-fold metallo-hydrolase domain
      pfam11718
      Location:486 → 687
      CPSF73-100_C; Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term

    2. NM_179504.2 → NP_849835.1  cleavage and polyadenylation specificity factor 73-I [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_849835.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8VY18, Q9C952
      UniProtKB/TrEMBL
      A0A178WGJ2, A0A5S9WN75, A0A7G2E2C2
      Conserved Domains (3) summary
      COG1236
      Location:24 → 462
      YSH1; RNA processing exonuclease, beta-lactamase fold, Cft2 family [Translation, ribosomal structure and biogenesis]
      cd16292
      Location:22 → 215
      CPSF3-like_MBL-fold; cleavage and polyadenylation specificity factor (CPSF) subunit 3 and related proteins; MBL-fold metallo-hydrolase domain
      pfam11718
      Location:486 → 687
      CPSF73-100_C; Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term

    3. NM_001333924.1 → NP_001319278.1  cleavage and polyadenylation specificity factor 73-I [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8VY18, Q9C952
      UniProtKB/TrEMBL
      A0A178WGJ2, A0A5S9WN75, A0A7G2E2C2
      Conserved Domains (3) summary
      COG1236
      Location:24 → 462
      YSH1; RNA processing exonuclease, beta-lactamase fold, Cft2 family [Translation, ribosomal structure and biogenesis]
      cd16292
      Location:22 → 215
      CPSF3-like_MBL-fold; cleavage and polyadenylation specificity factor (CPSF) subunit 3 and related proteins; MBL-fold metallo-hydrolase domain
      pfam11718
      Location:486 → 687
      CPSF73-100_C; Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term

    4. NM_001333925.1 → NP_001321253.1  cleavage and polyadenylation specificity factor 73-I [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8VY18, Q9C952
      UniProtKB/TrEMBL
      A0A178WGJ2, A0A5S9WN75, A0A7G2E2C2
      Conserved Domains (3) summary
      COG1236
      Location:24 → 462
      YSH1; RNA processing exonuclease, beta-lactamase fold, Cft2 family [Translation, ribosomal structure and biogenesis]
      cd16292
      Location:22 → 215
      CPSF3-like_MBL-fold; cleavage and polyadenylation specificity factor (CPSF) subunit 3 and related proteins; MBL-fold metallo-hydrolase domain
      pfam11718
      Location:486 → 687
      CPSF73-100_C; Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term

    5. NM_104782.4 → NP_176297.1  cleavage and polyadenylation specificity factor 73-I [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_176297.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8VY18, Q9C952
      UniProtKB/TrEMBL
      A0A178WGJ2, A0A5S9WN75, A0A7G2E2C2
      Conserved Domains (3) summary
      COG1236
      Location:24 → 462
      YSH1; RNA processing exonuclease, beta-lactamase fold, Cft2 family [Translation, ribosomal structure and biogenesis]
      cd16292
      Location:22 → 215
      CPSF3-like_MBL-fold; cleavage and polyadenylation specificity factor (CPSF) subunit 3 and related proteins; MBL-fold metallo-hydrolase domain
      pfam11718
      Location:486 → 687
      CPSF73-100_C; Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9C952.1

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