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    Clathrin adaptor complexes medium subunit family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 828557, updated on 18-Sep-2024

    Summary

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    Official Full Name
    Clathrin adaptor complexes medium subunit family protein
    Primary source
    TAIR:AT4G24550
    Locus tag
    AT4G24550
    See related
    Araport:AT4G24550
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    adaptor protein-4 mu-adaptin; AP4M; F22K18.250; F22K18_250
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    Genomic context

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    Location:
    chromosome: 4
    Exon count:
    13
    Sequence:
    Chromosome: 4; NC_003075.7 (12675708..12679203)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene O-fucosyltransferase family protein Neighboring gene AGAMOUS-like 24 Neighboring gene ubiquitin-specific protease 16 Neighboring gene tRNA-Ser Neighboring gene dicarboxylate carrier 2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Adaptor Complex AP-4 Regulates Vacuolar Protein Sorting at the trans-Golgi Network by Interacting with VACUOLAR SORTING RECEPTOR1. Fuji K, et al. Plant Physiol, 2016 Jan. PMID 26546666, Free PMC Article
    2. Global Analysis of Membrane-associated Protein Oligomerization Using Protein Correlation Profiling. McBride Z, et al. Mol Cell Proteomics, 2017 Nov. PMID 28887381, Free PMC Article
    3. Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana. Mayer K, et al. Nature, 1999 Dec 16. PMID 10617198

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    NM_001203895.1
    NM_118588.7
    NM_179106.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in intracellular protein transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in vesicle-mediated transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of AP-4 adaptor complex IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    part_of clathrin adaptor complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytosol HDA PubMed 
    located_in trans-Golgi network IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Clathrin adaptor complexes medium subunit family protein
    NP_001190824.1
    • Clathrin adaptor complexes medium subunit family protein; INVOLVED IN: intracellular protein transport, transport, vesicle-mediated transport; LOCATED IN: clathrin vesicle coat, clathrin adaptor complex; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Clathrin adaptor, mu subunit, C-terminal (InterPro:IPR008968), Clathrin adaptor, mu subunit (InterPro:IPR001392), Longin-like (InterPro:IPR011012); BEST Arabidopsis thaliana protein match is: Clathrin adaptor complexes medium subunit family protein (TAIR:AT1G10730.1).
    NP_194186.1
    • Clathrin adaptor complexes medium subunit family protein; INVOLVED IN: intracellular protein transport, transport, vesicle-mediated transport; LOCATED IN: clathrin vesicle coat, clathrin adaptor complex; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Clathrin adaptor, mu subunit, C-terminal (InterPro:IPR008968), Clathrin adaptor, mu subunit (InterPro:IPR001392), Longin-like (InterPro:IPR011012); BEST Arabidopsis thaliana protein match is: Clathrin adaptor complexes medium subunit family protein (TAIR:AT1G10730.1); Has 2068 Blast hits to 2032 proteins in 326 species: Archae - 0; Bacteria - 0; Metazoa - 1028; Fungi - 467; Plants - 203; Viruses - 0; Other Eukaryotes - 370 (source: NCBI BLink).
    NP_849437.1
    • Clathrin adaptor complexes medium subunit family protein; INVOLVED IN: intracellular protein transport, transport, vesicle-mediated transport; LOCATED IN: clathrin vesicle coat, clathrin adaptor complex; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Clathrin adaptor, mu subunit, C-terminal (InterPro:IPR008968), Clathrin adaptor, mu subunit (InterPro:IPR001392), Longin-like (InterPro:IPR011012); BEST Arabidopsis thaliana protein match is: Clathrin adaptor complexes medium subunit family protein (TAIR:AT1G60780.1); Has 2016 Blast hits to 1984 proteins in 326 species: Archae - 0; Bacteria - 0; Metazoa - 989; Fungi - 462; Plants - 201; Viruses - 0; Other Eukaryotes - 364 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      12675708..12679203
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_118588.7 → NP_194186.1  Clathrin adaptor complexes medium subunit family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_194186.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9SB50
      UniProtKB/TrEMBL
      A0A178UX13, A0A5S9XXN6
      Conserved Domains (2) summary
      cd09253
      Location:175 → 451
      AP-4_Mu4_Cterm; C-terminal domain of medium Mu4 subunit in adaptor protein (AP) complex AP-4
      cd14838
      Location:4 → 144
      AP4_Mu_N; AP-4 complex subunit mu N-terminal domain

    2. NM_179106.3 → NP_849437.1  Clathrin adaptor complexes medium subunit family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_849437.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      F4JQZ0
      Conserved Domains (2) summary
      cl02092
      Location:66 → 135
      Clat_adaptor_s; Clathrin adaptor complex small chain
      cl10970
      Location:175 → 374
      AP_MHD_Cterm; C-terminal domain of adaptor protein (AP) complexes medium mu subunits and its homologs (MHD)

    3. NM_001203895.1 → NP_001190824.1  Clathrin adaptor complexes medium subunit family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001190824.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      F4JQY9
      Conserved Domains (2) summary
      cl02092
      Location:66 → 135
      Clat_adaptor_s; Clathrin adaptor complex small chain
      cl10970
      Location:175 → 375
      AP_MHD_Cterm; C-terminal domain of adaptor protein (AP) complexes medium mu subunits and its homologs (MHD)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9SB50.1

    Gene LinkOut

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