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    NFU3 NFU domain protein 3 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 828697, updated on 18-Sep-2024

    Summary

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    Official Symbol
    NFU3
    Official Full Name
    NFU domain protein 3
    Primary source
    TAIR:AT4G25910
    Locus tag
    AT4G25910
    See related
    Araport:AT4G25910
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATCNFU3; F20B18.20; F20B18_20; NFU domain protein 3
    Summary
    Encodes a protein containing the NFU domain that may be involved in iron-sulfur cluster assembly. Part of a five member gene family, more closely related to NFU1 and 2 than to NFU4 and 5. Targeted to the chloroplast.
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    Genomic context

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    See NFU3 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    4
    Sequence:
    Chromosome: 4; NC_003075.7 (13163929..13165332)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene pumilio 6 Neighboring gene 60S acidic ribosomal protein family Neighboring gene Galactose mutarotase-like superfamily protein Neighboring gene hypothetical protein (DUF295) Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A Nitrogen-Fixing Subunit Essential for Accumulating 4Fe-4S-Containing Photosystem I Core Proteins. Nath K, et al. Plant Physiol, 2016 Dec. PMID 27784767, Free PMC Article
    2. Iron-sulfur protein NFU2 is required for branched-chain amino acid synthesis in Arabidopsis roots. Touraine B, et al. J Exp Bot, 2019 Mar 27. PMID 30785184
    3. The Arabidopsis chloroplastic NifU-like protein CnfU, which can act as an iron-sulfur cluster scaffold protein, is required for biogenesis of ferredoxin and photosystem I. Yabe T, et al. Plant Cell, 2004 Apr. PMID 15031412, Free PMC Article
    4. Iron-sulphur cluster assembly in plants: distinct NFU proteins in mitochondria and plastids from Arabidopsis thaliana. Léon S, et al. Biochem J, 2003 May 1. PMID 12553879, Free PMC Article
    5. 14-3-3 proteins fine-tune plant nutrient metabolism. Shin R, et al. FEBS Lett, 2011 Jan 3. PMID 21094157

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_118724.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables iron ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables iron-sulfur cluster binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables molecular adaptor activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables structural molecule activity TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within chloroplast organization ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    involved_in iron-sulfur cluster assembly IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within iron-sulfur cluster assembly IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within iron-sulfur cluster assembly ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    acts_upstream_of_or_within photosystem I assembly IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in chloroplast ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    located_in chloroplast stroma HDA PubMed 

    General protein information

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    Preferred Names
    NFU domain protein 3
    NP_567735.1
    • NFU domain protein 3 (NFU3); CONTAINS InterPro DOMAIN/s: NIF system FeS cluster assembly, NifU, C-terminal (InterPro:IPR001075); BEST Arabidopsis thaliana protein match is: NIFU-like protein 2 (TAIR:AT5G49940.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      13163929..13165332
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_118724.4 → NP_567735.1  NFU domain protein 3 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_567735.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q0WN92, Q84RQ7, Q8LCL7, Q9SZG6
      UniProtKB/TrEMBL
      A0A5S9XVW5, A0A654FSZ8, B9DGD5
      Conserved Domains (1) summary
      pfam01106
      Location:89 → 154
      NifU; NifU-like domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q84RQ7.1

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