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    ROPGEF7 RHO guanyl-nucleotide exchange factor 7 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 831858, updated on 18-Sep-2024

    Summary

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    Official Symbol
    ROPGEF7
    Official Full Name
    RHO guanyl-nucleotide exchange factor 7
    Primary source
    TAIR:AT5G02010
    Locus tag
    AT5G02010
    See related
    Araport:AT5G02010
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATROPGEF7; KINASE PARTNER PROTEIN-LIKE; KPP-LIKE; RHO guanyl-nucleotide exchange factor 7; ROP (rho of plants) guanine nucleotide exchange factor 7; T7H20.60; T7H20_60
    Summary
    Encodes a member of KPP-like gene family, homolog of KPP (kinase partner protein) gene in tomato. Also a member of the RopGEF (guanine nucleotide exchange factor) family, containing the novel PRONE domain (plant-specific Rop nucleotide exchanger), which is exclusively active towards members of the Rop subfamily.
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    Genomic context

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    See ROPGEF7 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    7
    Sequence:
    Chromosome: 5; NC_003076.8 (383153..385910)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene RING/U-box superfamily protein Neighboring gene Auxin efflux carrier family protein Neighboring gene uncharacterized protein Neighboring gene E3 ubiquitin-protein ligase RLIM-like protein Neighboring gene tRNA-Gly Neighboring gene POX (plant homeobox) family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. RopGEF7 regulates PLETHORA-dependent maintenance of the root stem cell niche in Arabidopsis. Chen M, et al. Plant Cell, 2011 Aug. PMID 21828289, Free PMC Article
    2. A Rho-based reaction-diffusion system governs cell wall patterning in metaxylem vessels. Nagashima Y, et al. Sci Rep, 2018 Aug 1. PMID 30069009, Free PMC Article
    3. Members of a novel class of Arabidopsis Rho guanine nucleotide exchange factors control Rho GTPase-dependent polar growth. Gu Y, et al. Plant Cell, 2006 Feb. PMID 16415208, Free PMC Article
    4. A new family of RhoGEFs activates the Rop molecular switch in plants. Berken A, et al. Nature, 2005 Aug 25. PMID 15980860
    5. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

    GeneRIFs: Gene References Into Functions

    General gene information

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    NM_120279.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables guanyl-nucleotide exchange factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within plant-type cell wall organization IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within plant-type cell wall organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    RHO guanyl-nucleotide exchange factor 7
    NP_195821.1
    • RHO guanyl-nucleotide exchange factor 7 (ROPGEF7); CONTAINS InterPro DOMAIN/s: Rop nucleotide exchanger, PRONE (InterPro:IPR005512); BEST Arabidopsis thaliana protein match is: ROP guanine nucleotide exchange factor 5 (TAIR:AT5G05940.1); Has 310 Blast hits to 307 proteins in 17 species: Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 0; Plants - 308; Viruses - 0; Other Eukaryotes - 2 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      383153..385910
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_120279.3 → NP_195821.1  RHO guanyl-nucleotide exchange factor 7 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_195821.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9LZN0
      UniProtKB/TrEMBL
      A0A178UPY8, A0A5S9Y109
      Conserved Domains (1) summary
      pfam03759
      Location:69 → 435
      PRONE; PRONE (Plant-specific Rop nucleotide exchanger)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LZN0.1

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