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    LAC12 laccase 12 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 830421, updated on 18-Sep-2024

    Summary

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    Official Symbol
    LAC12
    Official Full Name
    laccase 12
    Primary source
    TAIR:AT5G05390
    Locus tag
    AT5G05390
    See related
    Araport:AT5G05390
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    K18I23.20; K18I23_20; laccase 12
    Summary
    putative laccase, a member of laccase family of genes (17 members in Arabidopsis).
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    Genomic context

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    See LAC12 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    6
    Sequence:
    Chromosome: 5; NC_003076.8 (1594685..1597042)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene Heavy metal transport/detoxification superfamily protein Neighboring gene Cytochrome b-c1 complex, subunit 8 protein Neighboring gene prenylated RAB acceptor 1.B3 Neighboring gene LRR and NB-ARC domains-containing disease resistance protein Neighboring gene DRE-binding protein 2A Neighboring gene FKBP-like peptidyl-prolyl cis-trans isomerase family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Involvement of Arabidopsis Multi-Copper Oxidase-Encoding LACCASE12 in Root-to-Shoot Iron Partitioning: A Novel Example of Copper-Iron Crosstalk. Bernal M, et al. Front Plant Sci, 2021. PMID 34707625, Free PMC Article
    2. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

    GeneRIFs: Gene References Into Functions

    General gene information

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    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables copper ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables hydroquinone:oxygen oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in response to iron ion starvation IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular region ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    laccase 12
    NP_196158.1
    • laccase 12 (LAC12); FUNCTIONS IN: laccase activity; INVOLVED IN: oxidation reduction, lignin catabolic process; LOCATED IN: endomembrane system, apoplast; EXPRESSED IN: 7 plant structures; EXPRESSED DURING: petal differentiation and expansion stage; CONTAINS InterPro DOMAIN/s: Multicopper oxidase, type 3 (InterPro:IPR011707), Laccase (InterPro:IPR017761), Multicopper oxidase, type 2 (InterPro:IPR011706), Cupredoxin (InterPro:IPR008972), Multicopper oxidase, copper-binding site (InterPro:IPR002355), Multicopper oxidase, type 1 (InterPro:IPR001117); BEST Arabidopsis thaliana protein match is: laccase 5 (TAIR:AT2G40370.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      1594685..1597042
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_120621.2 → NP_196158.1  laccase 12 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_196158.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9FLB5
      UniProtKB/TrEMBL
      A0A5S9Y1N4, A0A654FYL2, A0A7G2F8J6
      Conserved Domains (1) summary
      TIGR03389
      Location:24 → 565
      laccase; plant
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9FLB5.1

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