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    RUP2 Transducin/WD40 repeat-like superfamily protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 832438, updated on 18-Sep-2024

    Summary

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    Official Symbol
    RUP2
    Official Full Name
    Transducin/WD40 repeat-like superfamily protein
    Primary source
    TAIR:AT5G23730
    Locus tag
    AT5G23730
    See related
    Araport:AT5G23730
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    EARLY FLOWERING BY OVEREXPRESSION 2; EFO2; MRO11.23; MRO11_23; REPRESSOR OF UV-B PHOTOMORPHOGENESIS 2
    Summary
    Encodes REPRESSOR OF UV-B PHOTOMORPHOGENESIS 2 (RUP2). Functions as a repressor of UV-B signaling.
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    Genomic context

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    See RUP2 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    1
    Sequence:
    Chromosome: 5; NC_003076.8 (8005097..8006630)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene coiled-coil protein Neighboring gene DNA binding / DNA-directed RNA polymerase Neighboring gene dual specificity protein phosphatase family protein Neighboring gene ncRNA Neighboring gene ribosomal protein S11-beta

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. RUP2 facilitates UVR8 redimerization via two interfaces. Wang L, et al. Plant Commun, 2023 Jan 9. PMID 36065466, Free PMC Article
    2. Arabidopsis RUP2 represses UVR8-mediated flowering in noninductive photoperiods. Arongaus AB, et al. Genes Dev, 2018 Oct 1. PMID 30254107, Free PMC Article
    3. EFO1 and EFO2, encoding putative WD-domain proteins, have overlapping and distinct roles in the regulation of vegetative development and flowering of Arabidopsis. Wang W, et al. J Exp Bot, 2011 Jan. PMID 21242318
    4. Regulation of UVR8 photoreceptor dimer/monomer photo-equilibrium in Arabidopsis plants grown under photoperiodic conditions. Findlay KM, et al. Plant Cell Environ, 2016 Aug. PMID 26864532, Free PMC Article
    5. Photoactivated UVR8-COP1 module determines photomorphogenic UV-B signaling output in Arabidopsis. Huang X, et al. PLoS Genet, 2014 Mar. PMID 24651064, Free PMC Article

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. RUP2 facilitates UVR8 redimerization via two interfaces.
      Title: RUP2 facilitates UVR8 redimerization via two interfaces.
    2. RUP2 functions as an essential repressor of UVR8-mediated induction of flowering under noninductive short day conditions and thus provides a crucial mechanism of photoperiodic flowering control.
      Title: Arabidopsis RUP2 represses UVR8-mediated flowering in noninductive photoperiods.
    3. crucial in regulating the UVR8 dimer/monomer photo-equilibrium, promotes reversion to the dimer
      Title: Regulation of UVR8 photoreceptor dimer/monomer photo-equilibrium in Arabidopsis plants grown under photoperiodic conditions.
    4. EFO1(At5g52250) and EFO2(At5g23730) have overlapping and distinct roles in vegetative development and flowering.
      Title: EFO1 and EFO2, encoding putative WD-domain proteins, have overlapping and distinct roles in the regulation of vegetative development and flowering of Arabidopsis.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_122278.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within chloroplast organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of protein-containing complex assembly IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within response to UV-B IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of Cul4-RING E3 ubiquitin ligase complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    Transducin/WD40 repeat-like superfamily protein
    NP_568435.2
    • Transducin/WD40 repeat-like superfamily protein; CONTAINS InterPro DOMAIN/s: WD40 repeat 2 (InterPro:IPR019782), WD40 repeat-like-containing domain (InterPro:IPR011046), WD40-repeat-containing domain (InterPro:IPR017986), WD40/YVTN repeat-like-containing domain (InterPro:IPR015943), WD40 repeat (InterPro:IPR001680), WD40 repeat, subgroup (InterPro:IPR019781); BEST Arabidopsis thaliana protein match is: Transducin/WD40 repeat-like superfamily protein (TAIR:AT5G52250.1); Has 12290 Blast hits to 8463 proteins in 487 species: Archae - 16; Bacteria - 2654; Metazoa - 3890; Fungi - 2899; Plants - 1307; Viruses - 0; Other Eukaryotes - 1524 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      8005097..8006630
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_122278.4 → NP_568435.2  Transducin/WD40 repeat-like superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_568435.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q94BR3, Q9FFA7
      UniProtKB/TrEMBL
      A0A178UGY8
      Conserved Domains (2) summary
      sd00039
      Location:46 → 82
      7WD40; WD40 repeat [structural motif]
      cl02567
      Location:41 → 362
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9FFA7.1

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