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    tral trailer hitch [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 39430, updated on 9-Dec-2024

    Summary

    Official Symbol
    tralprovided by FlyBase
    Official Full Name
    trailer hitchprovided by FlyBase
    Primary source
    FLYBASE:FBgn0041775
    Locus tag
    Dmel_CG10686
    See related
    AllianceGenome:FB:FBgn0041775
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    anon-EST:Posey139; anon-WO0172774.89; anon-WO02059370.24; BEST:GH08269; CG10686; Dmel\CG10686; DmLSm15; Lsm15; LSm15; p67; p70; Scd6p; Tral; TRAL
    Summary
    Enables DEAD/H-box RNA helicase binding activity. Involved in several processes, including cytoskeleton organization; positive regulation of determination of dorsal identity; and positive regulation of protein exit from endoplasmic reticulum. Located in cytoplasmic ribonucleoprotein granule and fusome. Colocalizes with endoplasmic reticulum. Is expressed in several structures, including adult brain cell body rind; adult head; central brain primordium; embryonic/larval midgut primordium; and ganglia. Orthologous to human LSM14B (LSM family member 14B) and LSM14A (LSM14A mRNA processing body assembly factor). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See tral in Genome Data Viewer
    Location:
    69C4-69C4; 3-38 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (12515059..12520954)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (12508159..12514054)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene vihar Neighboring gene sticky Neighboring gene long non-coding RNA:CR45168 Neighboring gene Gcn5 acetyltransferase Neighboring gene eukaryotic translation initiation factor 2 subunit beta Neighboring gene verrocchio

    Genomic regions, transcripts, and products

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables DEAD/H-box RNA helicase binding PubMed 
    enables RNA binding  
    enables mRNA binding  
    enables protein binding PubMed 
    Component Evidence Code Pubs
    located_in P granule PubMed 
    is_active_in P-body  
    located_in P-body PubMed 
    located_in cytosol PubMed 
    colocalizes_with endoplasmic reticulum PubMed 
    located_in fusome PubMed 
    located_in neuronal ribonucleoprotein granule PubMed 

    General protein information

    Preferred Names
    trailer hitch
    Names
    CG10686-PA
    CG10686-PB
    CG10686-PC
    CG10686-PD
    CG10686-PE
    CG10686-PF
    CG10686-PG
    CG10686-PH
    CG10686-PI
    Trailer-Hitch
    trailerhitch
    tral-PA
    tral-PB
    tral-PC
    tral-PD
    tral-PE
    tral-PF
    tral-PG
    tral-PH
    tral-PI

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      12515059..12520954
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001274842.1 → NP_001261771.1  trailer hitch, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001261771.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9PFF9
      Conserved Domains (2) summary
      cd01736
      Location:4 → 77
      LSm14_N; Like-Sm protein 14, N-terminal domain
      pfam09532
      Location:406 → 526
      FDF; FDF domain
    2. NM_001274840.1 → NP_001261769.1  trailer hitch, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001261769.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8T0T8, Q9VTZ0
      Conserved Domains (2) summary
      cd01736
      Location:4 → 77
      LSm14_N; Like-Sm protein 14, N-terminal domain
      pfam09532
      Location:402 → 532
      FDF; FDF domain
    3. NM_001274846.1 → NP_001261775.1  trailer hitch, isoform H [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001261775.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9PF20
      Conserved Domains (2) summary
      cd01736
      Location:4 → 77
      LSm14_N; Like-Sm protein 14, N-terminal domain
      pfam09532
      Location:406 → 536
      FDF; FDF domain
    4. NM_001274841.1 → NP_001261770.1  trailer hitch, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001261770.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9PF14
      Conserved Domains (2) summary
      cd01736
      Location:4 → 77
      LSm14_N; Like-Sm protein 14, N-terminal domain
      pfam09532
      Location:406 → 536
      FDF; FDF domain
    5. NM_001274847.1 → NP_001261776.1  trailer hitch, isoform I [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001261776.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9PFG3
      Conserved Domains (2) summary
      cd01736
      Location:4 → 77
      LSm14_N; Like-Sm protein 14, N-terminal domain
      pfam09532
      Location:406 → 526
      FDF; FDF domain
    6. NM_001274844.1 → NP_001261773.1  trailer hitch, isoform F [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001261773.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9PI44
      Conserved Domains (2) summary
      cd01736
      Location:4 → 77
      LSm14_N; Like-Sm protein 14, N-terminal domain
      pfam09532
      Location:402 → 532
      FDF; FDF domain
    7. NM_140328.5 → NP_648585.3  trailer hitch, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_648585.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8T0T8, Q9VTZ0
      Related
      FBpp0075691
      Conserved Domains (2) summary
      cd01736
      Location:4 → 77
      LSm14_N; Like-Sm protein 14, N-terminal domain
      pfam09532
      Location:402 → 532
      FDF; FDF domain
    8. NM_001274845.1 → NP_001261774.1  trailer hitch, isoform G [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001261774.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9PCB7
      Conserved Domains (2) summary
      cd01736
      Location:4 → 77
      LSm14_N; Like-Sm protein 14, N-terminal domain
      pfam09532
      Location:402 → 522
      FDF; FDF domain
    9. NM_001274843.1 → NP_001261772.1  trailer hitch, isoform E [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001261772.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9PFB2
      Conserved Domains (2) summary
      cd01736
      Location:4 → 77
      LSm14_N; Like-Sm protein 14, N-terminal domain
      pfam09532
      Location:402 → 522
      FDF; FDF domain
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