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    Pex11c Peroxin 11c [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 42751, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Pex11cprovided by FlyBase
    Official Full Name
    Peroxin 11cprovided by FlyBase
    Primary source
    FLYBASE:FBgn0039068
    Locus tag
    Dmel_CG13827
    See related
    AllianceGenome:FB:FBgn0039068
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:RE30473; CG13827; Dmel\CG13827; Pex11; PEX11C
    Summary
    Predicted to be involved in peroxisome fission. Located in peroxisome. Is expressed in several structures, including adult head; embryonic dorsal epidermis; embryonic epipharynx; embryonic hypopharynx; and gut section. Orthologous to human PEX11G (peroxisomal biogenesis factor 11 gamma). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Pex11c in Genome Data Viewer
    Location:
    94E9-94E9; 3-78 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (23258365..23260602)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (19084087..19086324)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Rad60 Neighboring gene Elongin A Neighboring gene will decrease acetylation Neighboring gene oo18 RNA-binding protein Neighboring gene Cell division cycle 16 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. NetREX-CF integrates incomplete transcription factor data with gene expression to reconstruct gene regulatory networks. Wang Y, et al. Commun Biol, 2022 Nov 23. PMID 36418514, Free PMC Article
    2. Peroxisome Elevation Induces Stem Cell Differentiation and Intestinal Epithelial Repair. Du G, et al. Dev Cell, 2020 Apr 20. PMID 32243783
    3. The essential gene wda encodes a WD40 repeat subunit of Drosophila SAGA required for histone H3 acetylation. Guelman S, et al. Mol Cell Biol, 2006 Oct. PMID 16980620, Free PMC Article
    4. A Systematic Cell-Based Analysis of Localization of Predicted Drosophila Peroxisomal Proteins. Baron MN, et al. Traffic, 2016 May. PMID 26865094
    5. Rosy Beginnings: Studying Peroxisomes in Drosophila. Pridie C, et al. Front Cell Dev Biol, 2020. PMID 32984330, Free PMC Article

    See all (30) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in peroxisome fission IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in peroxisome fission IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in peroxisomal membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in peroxisomal membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in peroxisome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in peroxisome ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    peroxin 11c
    Names
    CG13827-PA
    CG13827-PB
    Pex11c-PA
    Pex11c-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      23258365..23260602
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_142880.3 → NP_651137.3  peroxin 11c, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_651137.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8MZ03, Q9VCN8
      Related
      FBpp0083768
      Conserved Domains (1) summary
      pfam05648
      Location:8 → 225
      PEX11; Peroxisomal biogenesis factor 11 (PEX11)

    2. NM_001260334.1 → NP_001247263.1  peroxin 11c, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001247263.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4K701
      Conserved Domains (1) summary
      pfam05648
      Location:24 → 226
      PEX11; Peroxisomal biogenesis factor 11 (PEX11)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0A0B4K701 A0A0B4K701
    Q8MZ03 Q8MZ03

    Gene LinkOut

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