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    GATAd GATAd [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 34395, updated on 9-Dec-2024

    Summary

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    Official Symbol
    GATAdprovided by FlyBase
    Official Full Name
    GATAdprovided by FlyBase
    Primary source
    FLYBASE:FBgn0032223
    Locus tag
    Dmel_CG5034
    See related
    AllianceGenome:FB:FBgn0032223
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG5034; dGATA-D; dGATAd; Dmel\CG5034
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in cell fate commitment; negative regulation of transcription by RNA polymerase II; and positive regulation of transcription by RNA polymerase II. Located in nucleus. Is expressed in organism. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See GATAd in Genome Data Viewer
    Location:
    31D9-31D9; 2-41 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (10333734..10339185)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (10333734..10339185)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Schwannomin interacting protein 1 Neighboring gene Cytochrome c oxidase assembly factor 10 Neighboring gene S-adenosylmethionine decarboxylase Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The evolution of protostome GATA factors: molecular phylogenetics, synteny, and intron/exon structure reveal orthologous relationships. Gillis WQ, et al. BMC Evol Biol, 2008 Apr 15. PMID 18412965, Free PMC Article
    2. GATAe regulates intestinal stem cell maintenance and differentiation in Drosophila adult midgut. Okumura T, et al. Dev Biol, 2016 Feb 1. PMID 26719127
    3. DeepSTARR predicts enhancer activity from DNA sequence and enables the de novo design of synthetic enhancers. de Almeida BP, et al. Nat Genet, 2022 May. PMID 35551305
    4. Sex-specific transcriptomic responses to changes in the nutritional environment. Camus MF, et al. Elife, 2019 Aug 22. PMID 31436529, Free PMC Article
    5. An endoderm-specific GATA factor gene, dGATAe, is required for the terminal differentiation of the Drosophila endoderm. Okumura T, et al. Dev Biol, 2005 Feb 15. PMID 15680371

    See all (47) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables DNA-binding transcription factor activity, RNA polymerase II-specific ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in cell fate commitment IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in negative regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in positive regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    GATAd
    Names
    CG5034-PA
    CG5034-PB
    CG5034-PC
    GATAd-PA
    GATAd-PB
    GATAd-PC

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      10333734..10339185
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001273397.1 → NP_001260326.1  GATAd, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001260326.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VKZ0
      Conserved Domains (3) summary
      smart00401
      Location:688 → 736
      ZnF_GATA; zinc finger binding to DNA consensus sequence [AT]GATA[AG]
      smart00868
      Location:228 → 284
      zf-AD; Zinc-finger associated domain (zf-AD)
      cd00202
      Location:691 → 742
      ZnF_GATA; Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C

    2. NM_001273398.1 → NP_001260327.1  GATAd, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001260327.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VKZ0
      Conserved Domains (3) summary
      smart00401
      Location:688 → 736
      ZnF_GATA; zinc finger binding to DNA consensus sequence [AT]GATA[AG]
      smart00868
      Location:228 → 284
      zf-AD; Zinc-finger associated domain (zf-AD)
      cd00202
      Location:691 → 742
      ZnF_GATA; Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C

    3. NM_135539.3 → NP_609383.2  GATAd, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_609383.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VKZ0
      Related
      FBpp0079583
      Conserved Domains (3) summary
      smart00401
      Location:688 → 736
      ZnF_GATA; zinc finger binding to DNA consensus sequence [AT]GATA[AG]
      smart00868
      Location:228 → 284
      zf-AD; Zinc-finger associated domain (zf-AD)
      cd00202
      Location:691 → 742
      ZnF_GATA; Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q95TF1 Q95TF1
    Q9BPQ1 Q9BPQ1
    Q9VKZ0 Q9VKZ0

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