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    Cpr57A Cuticular protein 57A [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 37319, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Cpr57Aprovided by FlyBase
    Official Full Name
    Cuticular protein 57Aprovided by FlyBase
    Primary source
    FLYBASE:FBgn0034517
    Locus tag
    Dmel_CG18066
    See related
    AllianceGenome:FB:FBgn0034517
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG18066; Dmel\CG18066
    Summary
    Predicted to be a structural constituent of chitin-based larval cuticle. Predicted to be involved in chitin-based cuticle development. Predicted to be located in chitin-based extracellular matrix. Predicted to be active in extracellular matrix. Is expressed in eye. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Cpr57A in Genome Data Viewer
    Location:
    57A5-57A5; 2-91 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (20548368..20550117, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (16435873..16437622, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Odorant-binding protein 57e Neighboring gene Odorant-binding protein 57d Neighboring gene uncharacterized protein Neighboring gene BLOC-1 related complex subunit 7 Neighboring gene lateral muscles scarcer Neighboring gene Mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Odorant-binding proteins OBP57d and OBP57e affect taste perception and host-plant preference in Drosophila sechellia. Matsuo T, et al. PLoS Biol, 2007 May. PMID 17456006, Free PMC Article
    2. Rapid evolution of two odorant-binding protein genes, Obp57d and Obp57e, in the Drosophila melanogaster species group. Matsuo T. Genetics, 2008 Feb. PMID 18245367, Free PMC Article
    3. A Search for Genes Mediating the Growth-Promoting Function of TGFβ in the Drosophila melanogaster Wing Disc. Hevia CF, et al. Genetics, 2017 May. PMID 28315837, Free PMC Article
    4. Interactions with ectoparasitic mites induce host metabolic and immune responses in flies at the expense of reproduction-associated factors. Benoit JB, et al. Parasitology, 2020 Sep. PMID 32498733, Free PMC Article
    5. A lysosomal tetraspanin associated with retinal degeneration identified via a genome-wide screen. Xu H, et al. EMBO J, 2004 Feb 25. PMID 14963491, Free PMC Article

    See all (30) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables structural constituent of chitin-based larval cuticle ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in chitin-based cuticle development ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chitin-based extracellular matrix ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    is_active_in extracellular matrix IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    cuticular protein 57A
    Names
    CG18066-PA
    CG18066-PB
    Cpr57A-PA
    Cpr57A-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      20548368..20550117 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001144249.2 → NP_001137721.1  cuticular protein 57A, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001137721.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7K5J8
      Conserved Domains (1) summary
      pfam00379
      Location:32 → 84
      Chitin_bind_4; Insect cuticle protein

    2. NM_137645.3 → NP_611489.1  cuticular protein 57A, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_611489.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7K5J8
      Related
      FBpp0085575
      Conserved Domains (1) summary
      pfam00379
      Location:32 → 84
      Chitin_bind_4; Insect cuticle protein
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q7K5J8 Q7K5J8

    Gene LinkOut

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