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    Sr-CIII Scavenger receptor class C, type III [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 44382, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Sr-CIIIprovided by FlyBase
    Official Full Name
    Scavenger receptor class C, type IIIprovided by FlyBase
    Primary source
    FLYBASE:FBgn0020376
    Locus tag
    Dmel_CG31962
    See related
    AllianceGenome:FB:FBgn0020376
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG31962; Dmel\CG31962; dSR-CIII; SR-CIII
    Summary
    Predicted to be involved in nervous system development. Predicted to be located in membrane. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
    NEW
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    Genomic context

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    See Sr-CIII in Genome Data Viewer
    Location:
    24D6-24D6; 2-11 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (4120343..4121627)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (4120343..4121627)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene echinoid Neighboring gene antisense RNA:CR44984 Neighboring gene Scavenger receptor class C, type I Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Expression cloning of dSR-CI, a class C macrophage-specific scavenger receptor from Drosophila melanogaster. Pearson A, et al. Proc Natl Acad Sci U S A, 1995 Apr 25. PMID 7732030, Free PMC Article
    2. Linkage disequilibrium and recent selection at three immunity receptor loci in Drosophila simulans. Schlenke TA, et al. Genetics, 2005 Apr. PMID 15654108, Free PMC Article
    3. Elevated polymorphism and divergence in the class C scavenger receptors of Drosophila melanogaster and D. simulans. Lazzaro BP. Genetics, 2005 Apr. PMID 15716507, Free PMC Article
    4. New genes in Drosophila quickly become essential. Chen S, et al. Science, 2010 Dec 17. PMID 21164016, Free PMC Article
    5. Genetic basis of natural variation in D. melanogaster antibacterial immunity. Lazzaro BP, et al. Science, 2004 Mar 19. PMID 15031506

    See all (33) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Hmu, Sr-CI/Sr-CIII, and Tehao have polymorphic sites in nearly perfect linkage disequilibrium
      Title: Linkage disequilibrium and recent selection at three immunity receptor loci in Drosophila simulans.
    Submit: New GeneRIF Correction

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by FlyBase

    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    scavenger receptor class C, type III
    Names
    CG31962-PA
    Sr-CIII-PA
    scavenger receptor

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      4120343..4121627
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_080008.2 → NP_524747.1  scavenger receptor class C, type III [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_524747.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q5ELU7, Q9N2Q3
      Related
      FBpp0077155
      Conserved Domains (3) summary
      cd06263
      Location:143 → 310
      MAM; Meprin, A5 protein, and protein tyrosine phosphatase Mu (MAM) domain. MAM is an extracellular domain which mediates protein-protein interactions and is found in a diverse set of proteins, many of which are known to function in cell adhesion. Members ...
      cd00033
      Location:27 → 62
      CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system
      pfam00629
      Location:143 → 310
      MAM; MAM domain, meprin/A5/mu
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5ELR6 Q5ELR6
    Q5ELS0 Q5ELS0
    Q5ELS2 Q5ELS2
    Q5ELS4 Q5ELS4
    Q5ELS6 Q5ELS6
    Q5ELS9 Q5ELS9
    Q5ELT1 Q5ELT1
    Q5ELU3 Q5ELU3
    Q5ELU7 Q5ELU7
    Q5ELU9 Q5ELU9
    Q9N2Q3 Q9N2Q3

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