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    mrva minerva [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 38808, updated on 9-Dec-2024

    Summary

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    Official Symbol
    mrvaprovided by FlyBase
    Official Full Name
    minervaprovided by FlyBase
    Primary source
    FLYBASE:FBgn0035763
    Locus tag
    Dmel_CG8602
    See related
    AllianceGenome:FB:FBgn0035763
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    anon-WO0118547.349; anon-WO0118547.382; CG8602; Dmel\CG8602
    Summary
    Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Is active in Golgi membrane and endosome. Is expressed in several structures, including adult head; adult heart; amnioserosa; plasmatocyte primordium; and yolk nucleus. Orthologous to human MFSD1 (major facilitator superfamily domain containing 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See mrva in Genome Data Viewer
    Location:
    65F4-65F4; 3-20 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (7326273..7328842, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (7319373..7321942, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Rho guanine nucleotide exchange factor 4 Neighboring gene RAD50 interactor 1 Neighboring gene uncharacterized protein Neighboring gene mutagen-sensitive 312 Neighboring gene wurmchen 1 Neighboring gene wurmchen 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A conserved major facilitator superfamily member orchestrates a subset of O-glycosylation to aid macrophage tissue invasion. Valoskova K, et al. Elife, 2019 Mar 26. PMID 30910009, Free PMC Article
    2. Glucose Availability Alters Gene and Protein Expression of Several Newly Classified and Putative Solute Carriers in Mice Cortex Cell Culture and D. melanogaster. Ceder MM, et al. Front Cell Dev Biol, 2020. PMID 32733888, Free PMC Article
    3. The Identification and Evolutionary Trends of the Solute Carrier Superfamily in Arthropods. Denecke SM, et al. Genome Biol Evol, 2020 Aug 1. PMID 32681801, Free PMC Article
    4. Identification of Genes Involved in the Differentiation of R7y and R7p Photoreceptor Cells in Drosophila. Earl JB, et al. G3 (Bethesda), 2020 Nov 5. PMID 32972998, Free PMC Article
    5. Retroposed new genes out of the X in Drosophila. Betrán E, et al. Genome Res, 2002 Dec. PMID 12466289, Free PMC Article

    See all (37) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables transmembrane transporter activity ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in transmembrane transport ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in Golgi membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in endosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in lysosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in membrane ISM
    Inferred from Sequence Model
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    minerva
    Names
    CG8602-PA
    CG8602-PB
    mrva-PA
    mrva-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      7326273..7328842 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_139846.3 → NP_648103.1  minerva, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_648103.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VS47
      Related
      FBpp0076594
      Conserved Domains (2) summary
      cd06174
      Location:55 → 448
      MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
      pfam07690
      Location:58 → 410
      MFS_1; Major Facilitator Superfamily

    2. NM_001274576.1 → NP_001261505.1  minerva, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001261505.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VS47
      Conserved Domains (2) summary
      cd06174
      Location:55 → 448
      MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
      pfam07690
      Location:58 → 410
      MFS_1; Major Facilitator Superfamily
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VS47 Q9VS47

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