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    PIG-Z Phosphatidylinositol glycan anchor biosynthesis class Z [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 19835548, updated on 9-Dec-2024

    Summary

    Official Symbol
    PIG-Zprovided by FlyBase
    Official Full Name
    Phosphatidylinositol glycan anchor biosynthesis class Zprovided by FlyBase
    Primary source
    FLYBASE:FBgn0266438
    Locus tag
    Dmel_CG45068
    See related
    AllianceGenome:FB:FBgn0266438
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG3419; CG45068; Dmel\CG45068; PIGZ
    Summary
    Predicted to enable alpha-1,2-mannosyltransferase activity. Predicted to be involved in GPI anchor biosynthetic process. Predicted to be located in endoplasmic reticulum. Predicted to be active in endoplasmic reticulum membrane. Is expressed in adult head. Orthologous to human PIGZ (phosphatidylinositol glycan anchor biosynthesis class Z). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See PIG-Z in Genome Data Viewer
    Location:
    60C8-60C8; 2-106 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (24411870..24415295)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (20299393..20302818)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene Sterile20-like kinase Neighboring gene Regulatory particle non-ATPase 8 Neighboring gene Serotonin transporter Neighboring gene uncharacterized protein Neighboring gene prominin Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables alpha-1,2-mannosyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables alpha-1,2-mannosyltransferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables glycosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables mannosyltransferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Process Evidence Code Pubs
    involved_in GPI anchor biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in GPI anchor biosynthetic process ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    located_in endoplasmic reticulum ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    is_active_in endoplasmic reticulum membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    phosphatidylinositol glycan anchor biosynthesis class Z
    Names
    CG45068-PA
    PIG-Z-PA
    NP_001286840.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      24411870..24415295
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001299911.1NP_001286840.1  phosphatidylinositol glycan anchor biosynthesis class Z [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001286840.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A0A0B4LGH6, Q8MT80, Q9W176
      Conserved Domains (1) summary
      pfam03901
      Location:18541
      Glyco_transf_22; Alg9-like mannosyltransferase family