Pcdhb21 protocadherin beta 21 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Pcdhb21provided by MGI
Official Full Name: protocadherin beta 21provided by MGI
Primary source: MGI:MGI:2136759
See related: Ensembl:ENSMUSG00000044022 AllianceGenome:MGI:2136759
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: PcdhbU; Pcdhb18
Summary: Predicted to be involved in cell adhesion. Predicted to be active in plasma membrane. Is expressed in brain; cerebral cortex; and embryo. Orthologous to several human genes including PCDHB18P (protocadherin beta 18 pseudogene). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

Location:: 18 B3; 18 19.51 cM

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	18	NC_000084.7 (37646678..37650260)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	18	NC_000084.6 (37513652..37516363)

Chromosome 18 - NC_000084.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (1)

General gene information

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Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
involved_in cell adhesion	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: protocadherin beta 21

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_053146.3 → NP_444376.1 protocadherin beta 21 precursor

See identical proteins and their annotated locations for NP_444376.1

Status: VALIDATED

Source sequence(s)

AC020967

Consensus CDS

CCDS29186.1

UniProtKB/TrEMBL

Q3UYA2, Q91V48

Related

ENSMUSP00000056424.5, ENSMUST00000061405.6

Conserved Domains (4) summary

cd11304
Location:245 → 341

Cadherin_repeat; Cadherin tandem repeat domain

smart00112
Location:370 → 448

CA; Cadherin repeats

pfam08266
Location:30 → 110

Cadherin_2; Cadherin-like

pfam16492
Location:687 → 769

Cadherin_C_2; Cadherin cytoplasmic C-terminal