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    eccCb1 ESX-1 secretion system protein EccCb [ Mycobacterium tuberculosis H37Rv ]

    Gene ID: 886202, updated on 6-Oct-2023

    Summary

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    Gene symbol
    eccCb1
    Gene description
    ESX-1 secretion system protein EccCb
    Locus tag
    Rv3871
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mycobacterium tuberculosis H37Rv (strain: H37Rv, type-material: type strain of Mycobacterium tuberculosis)
    Lineage
    Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex
    Also known as
    snm2
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    Genomic context

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    Sequence:
    NC_000962.3 (4348827..4350602)

    NC_000962.3Genomic Context describing neighboring genes Neighboring gene ESX-1 secretion system protein EccB Neighboring gene ESX-1 secretion system protein EccCa Neighboring gene PE family protein PE35 Neighboring gene PPE family protein PPE68

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000962.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. [Cloning, expression and bioinformatic analysis of Rv3871 gene related to Mycobacterium tuberculosis virulent protein secretion]. Bao YG, et al. Nan Fang Yi Ke Da Xue Xue Bao, 2009 Dec. PMID 20034878
    2. Polymorphism in the RD1 locus and its effect on downstream genes among South Indian clinical isolates of Mycobacterium tuberculosis. Refaya AK, et al. J Med Microbiol, 2012 Oct. PMID 22723257
    3. Binding of the Mycobacterium tuberculosis EccCb1 ATPase double hexameric ring to the EsxAB virulence factor is enhanced by ATP. Bandyopadhyay A, et al. Biochem J, 2022 Jul 29. PMID 35770799
    4. A mycobacterium ESX-1-secreted virulence factor with unique requirements for export. McLaughlin B, et al. PLoS Pathog, 2007 Aug 3. PMID 17676952, Free PMC Article
    5. TubercuList--10 years after. Lew JM, et al. Tuberculosis (Edinb), 2011 Jan. PMID 20980199

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Binding of the Mycobacterium tuberculosis EccCb1 ATPase double hexameric ring to the EsxAB virulence factor is enhanced by ATP.
      Title: Binding of the Mycobacterium tuberculosis EccCb1 ATPase double hexameric ring to the EsxAB virulence factor is enhanced by ATP.
    2. Higher transcription levels of Rv3871 were observed in strains with four copies of the repeat element in the upstream region.
      Title: Polymorphism in the RD1 locus and its effect on downstream genes among South Indian clinical isolates of Mycobacterium tuberculosis.
    3. Rv3871 contains two FtsK/SpoE III domains, and has distinct differences between pathogenic and non-pathogenic mycobacteria.
      Title: [Cloning, expression and bioinformatic analysis of Rv3871 gene related to Mycobacterium tuberculosis virulent protein secretion].
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    General protein information

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    Preferred Names
    ESX-1 secretion system protein EccCb

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000962.3 Reference assembly

      Range
      4348827..4350602
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_218388.1 ESX-1 secretion system protein EccCb [Mycobacterium tuberculosis H37Rv]

      See identical proteins and their annotated locations for NP_218388.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A654TKP1
      Conserved Domains (1) summary
      TIGR03925
      Location:9 → 574
      T7SS_EccC_b; type VII secretion protein EccCb
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P9WNB1.1

    Gene LinkOut

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