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    bacA vitamin B12 transport ATP-binding protein BacA [ Mycobacterium tuberculosis H37Rv ]

    Gene ID: 885539, updated on 6-Oct-2023

    Summary

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    Gene symbol
    bacA
    Gene description
    vitamin B12 transport ATP-binding protein BacA
    Locus tag
    Rv1819c
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mycobacterium tuberculosis H37Rv (strain: H37Rv, type-material: type strain of Mycobacterium tuberculosis)
    Lineage
    Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex
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    Genomic context

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    Sequence:
    NC_000962.3 (2062809..2064728, complement)

    NC_000962.3Genomic Context describing neighboring genes Neighboring gene flavoprotein Neighboring gene PE-PGRS family protein PE_PGRS33 Neighboring gene acetolactate synthase large subunit IlvG Neighboring gene accessory Sec system translocase SecA2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000962.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A mycobacterial ABC transporter mediates the uptake of hydrophilic compounds. Rempel S, et al. Nature, 2020 Apr. PMID 32296172
    2. BacA, an ABC transporter involved in maintenance of chronic murine infections with Mycobacterium tuberculosis. Domenech P, et al. J Bacteriol, 2009 Jan. PMID 18996991, Free PMC Article
    3. TubercuList--10 years after. Lew JM, et al. Tuberculosis (Edinb), 2011 Jan. PMID 20980199
    4. Re-annotation of the genome sequence of Mycobacterium tuberculosis H37Rv. Camus JC, et al. Microbiology (Reading), 2002 Oct. PMID 12368430
    5. Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Cole ST, et al. Nature, 1998 Jun 11. PMID 9634230

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Rv1819c is a multi-solute transporter for hydrophilic molecules, analogous to the multidrug exporters of the ABC transporter family
      Title: A mycobacterial ABC transporter mediates the uptake of hydrophilic compounds.
    2. BacA is involved in maintenance of chronic mice infections.
      Title: BacA, an ABC transporter involved in maintenance of chronic murine infections with Mycobacterium tuberculosis.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    General protein information

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    Preferred Names
    vitamin B12 transport ATP-binding protein BacA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000962.3 Reference assembly

      Range
      2062809..2064728 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_216335.1 vitamin B12 transport ATP-binding protein BacA [Mycobacterium tuberculosis H37Rv]

      See identical proteins and their annotated locations for NP_216335.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A655ALT5
      Conserved Domains (1) summary
      COG4178
      Location:22 → 639
      YddA; ABC-type uncharacterized transport system, permease and ATPase components [General function prediction only]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P9WQI9.1

    Gene LinkOut

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