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    Ppt2 Palmitoyl-protein Thioesterase 2 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 34564, updated on 9-Dec-2024

    Summary

    Official Symbol
    Ppt2provided by FlyBase
    Official Full Name
    Palmitoyl-protein Thioesterase 2provided by FlyBase
    Primary source
    FLYBASE:FBgn0032358
    Locus tag
    Dmel_CG4851
    See related
    AllianceGenome:FB:FBgn0032358
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG4851; Dmel\CG4851; PPT-2
    Summary
    Enables palmitoyl-(protein) hydrolase activity. Located in lysosome. Is expressed in adult heart; larval brain; larval central nervous system; and organism. Orthologous to human PPT2 (palmitoyl-protein thioesterase 2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See Ppt2 in Genome Data Viewer
    Location:
    32E2-32E2; 2-44 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (11280298..11281920)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (11280298..11281920)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene CENP-ana Neighboring gene uncharacterized protein Neighboring gene antisense RNA:CR44182 Neighboring gene meiotic recombination 11 Neighboring gene Osiris 21 Neighboring gene long non-coding RNA:CR43409

    Genomic regions, transcripts, and products

    Pathways from PubChem

    Interactions

    General gene information

    Gene Ontology Provided by FlyBase

    Component Evidence Code Pubs
    is_active_in extracellular region  
    is_active_in lysosome  
    located_in lysosome PubMed 

    General protein information

    Preferred Names
    Palmitoyl-protein thioesterase 2
    Names
    CG4851-PA
    Ppt2-PA
    NP_609500.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      11280298..11281920
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_135656.3 → NP_609500.1  Palmitoyl-protein thioesterase 2 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_609500.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q95SL2, Q9VKH6
      Related
      FBpp0079801
      Conserved Domains (1) summary
      cl21494
      Location:25 → 262
      Abhydrolase; alpha/beta hydrolases
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