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    CG7742 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 33750, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG7742provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0031690
    Locus tag
    Dmel_CG7742
    See related
    AllianceGenome:FB:FBgn0031690
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG7742
    Summary
    Predicted to enable GTPase activator activity. Orthologous to human TBC1D19 (TBC1 domain family member 19). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG7742 in Genome Data Viewer
    Location:
    25C10-25D1; 2-16 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (5212395..5215081, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (5212395..5215081, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Muscle-specific protein 300 kDa Neighboring gene small non-coding RNA 158 Neighboring gene Cytochrome P450 28d2 Neighboring gene Cytochrome P450 28d1 Neighboring gene uncharacterized protein Neighboring gene Troponin C at 25D Neighboring gene thickveins

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Structural variants exhibit widespread allelic heterogeneity and shape variation in complex traits. Chakraborty M, et al. Nat Commun, 2019 Oct 25. PMID 31653862, Free PMC Article
    2. Molecular effects of dADD1 misexpression in chromatin organization and transcription. Meyer-Nava S, et al. BMC Mol Cell Biol, 2020 Mar 23. PMID 32293240, Free PMC Article
    3. Evolution of Tre-2/Bub2/Cdc16 (TBC) Rab GTPase-activating proteins. Gabernet-Castello C, et al. Mol Biol Cell, 2013 May. PMID 23485563, Free PMC Article
    4. Evi5 promotes collective cell migration through its Rab-GAP activity. Laflamme C, et al. J Cell Biol, 2012 Jul 9. PMID 22778279, Free PMC Article
    5. Decoding cilia function: defining specialized genes required for compartmentalized cilia biogenesis. Avidor-Reiss T, et al. Cell, 2004 May 14. PMID 15137945

    See all (30) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables GTPase activator activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG7742-PA
    CG7742-PB
    CG7742-PC
    CG7742-PD

    NCBI Reference Sequences (RefSeq)

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    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      5212395..5215081 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001298686.1 → NP_001285615.1  uncharacterized protein Dmel_CG7742, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001285615.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VMT4
      Conserved Domains (1) summary
      smart00164
      Location:249 → 478
      TBC; Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs

    2. NM_001298688.1 → NP_001285617.1  uncharacterized protein Dmel_CG7742, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001285617.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VMT4
      Conserved Domains (1) summary
      smart00164
      Location:249 → 478
      TBC; Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs

    3. NM_135069.3 → NP_608913.1  uncharacterized protein Dmel_CG7742, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_608913.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VMT4
      Related
      FBpp0078725
      Conserved Domains (1) summary
      smart00164
      Location:249 → 478
      TBC; Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs

    4. NM_001298687.1 → NP_001285616.1  uncharacterized protein Dmel_CG7742, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001285616.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      X2J8N3
      Conserved Domains (1) summary
      smart00164
      Location:181 → 410
      TBC; Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VMT4 Q9VMT4
    X2J8N3 X2J8N3

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