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    ana anachronism [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 35913, updated on 17-Dec-2024

    Summary

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    Official Symbol
    anaprovided by FlyBase
    Official Full Name
    anachronismprovided by FlyBase
    Primary source
    FLYBASE:FBgn0011746
    Locus tag
    Dmel_CG8084
    See related
    AllianceGenome:FB:FBgn0011746
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Ana; CG8084; Dmel\CG8084; med
    Summary
    Involved in negative regulation of neuroblast proliferation. Is expressed in several structures, including adult optic lobe; ganglia; larval central nervous system; mesonotum; and presumptive embryonic/larval central nervous system. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See ana in Genome Data Viewer
    Location:
    45A1-45A1; 2-60 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (9062295..9077554)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (4949800..4965059)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene Prophenoloxidase 2 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene antisense RNA:CR45924 Neighboring gene Concentrative nucleoside transporter 2 Neighboring gene Concentrative nucleoside transporter 1 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Drosophila anachronism locus: a glycoprotein secreted by glia inhibits neuroblast proliferation. Ebens AJ, et al. Cell, 1993 Jul 16. PMID 7916657
    2. Mutation of the central nervous system neuroblast proliferation repressor ana leads to defects in larval olfactory behavior. Park Y, et al. J Neurobiol, 1997 Aug. PMID 9240375
    3. Sleeping neuroblasts. Meinertzhagen IA. Curr Biol, 1993 Dec 1. PMID 15335832
    4. Control of proliferation activation in quiescent neuroblasts of the Drosophila central nervous system. Datta S. Development, 1995 Apr. PMID 7743929
    5. Environmental control of the cell cycle in Drosophila: nutrition activates mitotic and endoreplicative cells by distinct mechanisms. Britton JS, et al. Development, 1998 Jun. PMID 9570778

    See all (72) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in negative regulation of neuroblast proliferation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    anachronism
    Names
    CG8084-PA
    CG8084-PB
    CG8084-PC
    ana-PA
    ana-PB
    ana-PC
    medullaless

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      9062295..9077554
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001299297.1 → NP_001286226.1  anachronism, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001286226.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4LFV7

    2. NM_001169622.2 → NP_001163093.1  anachronism, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001163093.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      E1JH14

    3. NM_057690.3 → NP_477038.1  anachronism, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_477038.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q26307, Q9V524
      UniProtKB/TrEMBL
      G4LU48
      Related
      FBpp0087642
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0A0B4LFV7 A0A0B4LFV7
    E1JH14 E1JH14
    Q26307.2 Q26307
    Q95TB3 Q95TB3

    Gene LinkOut

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