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    CG13502 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 37518, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG13502provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0034692
    Locus tag
    Dmel_CG13502
    See related
    AllianceGenome:FB:FBgn0034692
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG13502
    Summary
    Predicted to be involved in cilium assembly and cilium movement. Predicted to be located in axoneme. Is expressed in chordotonal neurons. Human ortholog(s) of this gene implicated in primary ciliary dyskinesia 35. Orthologous to human ODAD4 (outer dynein arm docking complex subunit 4). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG13502 in Genome Data Viewer
    Location:
    58B4-58B5; 2-98 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (22085782..22088727, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (17973287..17976232, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene Glucosylceramide synthase Neighboring gene Synaptojanin Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Synaptojanin is recruited by endophilin to promote synaptic vesicle uncoating. Verstreken P, et al. Neuron, 2003 Nov 13. PMID 14622578
    2. WIP/WASp-based actin-polymerization machinery is essential for myoblast fusion in Drosophila. Massarwa R, et al. Dev Cell, 2007 Apr. PMID 17419994
    3. Survey of the Ciliary Motility Machinery of Drosophila Sperm and Ciliated Mechanosensory Neurons Reveals Unexpected Cell-Type Specific Variations: A Model for Motile Ciliopathies. Zur Lage P, et al. Front Genet, 2019. PMID 30774648, Free PMC Article
    4. Laser microdissection of sensory organ precursor cells of Drosophila microchaetes. Buffin E, et al. PLoS One, 2010 Feb 19. PMID 20174573, Free PMC Article
    5. Time-resolved mapping of genetic interactions to model rewiring of signaling pathways. Heigwer F, et al. Elife, 2018 Dec 28. PMID 30592458, Free PMC Article

    See all (26) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in cilium assembly ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in cilium movement ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    located_in axoneme ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG13502-PA
    CG13502-PD

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      22085782..22088727 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001259526.2 → NP_001246455.1  uncharacterized protein Dmel_CG13502, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001246455.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      D6W4X6
      Conserved Domains (2) summary
      sd00006
      Location:18 → 46
      TPR; TPR repeat [structural motif]
      pfam13414
      Location:17 → 79
      TPR_11; TPR repeat

    2. NM_137793.2 → NP_611637.1  uncharacterized protein Dmel_CG13502, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_611637.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9W295
      Related
      FBpp0071712
      Conserved Domains (2) summary
      sd00006
      Location:165 → 189
      TPR; TPR repeat [structural motif]
      pfam12895
      Location:174 → 252
      ANAPC3; Anaphase-promoting complex, cyclosome, subunit 3
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    D6W4X6 D6W4X6
    Q9W295 Q9W295

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