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    CkIIbeta2 Casein kinase II beta2 subunit [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 37300, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CkIIbeta2provided by FlyBase
    Official Full Name
    Casein kinase II beta2 subunitprovided by FlyBase
    Primary source
    FLYBASE:FBgn0026136
    Locus tag
    Dmel_CG8914
    See related
    AllianceGenome:FB:FBgn0026136
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG8914; CK2; CK2beta'; CKIIb2; CKIIbeta'; CKIIbeta2; dCK2beta'; Dm-CK2-beta'; DmCK2beta'; DmCKIIbeta'; Dmel\CG8914
    Summary
    Predicted to enable protein kinase regulator activity. Predicted to be part of protein kinase CK2 complex. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CkIIbeta2 in Genome Data Viewer
    Location:
    56F16-56F16; 2-90 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (20289545..20290550)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (16177050..16178055)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Cuticular protein 56F Neighboring gene long non-coding RNA:CR44638 Neighboring gene long non-coding RNA:CR44639

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A gene located at 56F1-2 in Drosophila melanogaster encodes a novel metazoan beta-like subunit of casein kinase II. Bidwai AP, et al. Mol Cell Biol Res Commun, 1999 Apr. PMID 10329473
    2. A gene located at 72A in Drosophila melanogaster encodes a novel zinc-finger protein that interacts with protein kinase CK2. Kalive M, et al. Mol Cell Biochem, 2001 Nov. PMID 11827180
    3. Drosophila protein kinase CK2 is rendered temperature-sensitive by mutations of highly conserved residues flanking the activation segment. Kuntamalla PP, et al. Mol Cell Biochem, 2009 Mar. PMID 19039653, Free PMC Article
    4. CK2(beta)tes gene encodes a testis-specific isoform of the regulatory subunit of casein kinase 2 in Drosophila melanogaster. Kalmykova AI, et al. Eur J Biochem, 2002 Mar. PMID 11874456
    5. The Drosophila SSL gene is expressed in larvae, pupae, and adults, exhibits sexual dimorphism, and mimics properties of the beta subunit of casein kinase II. Karandikar U, et al. Biochem Biophys Res Commun, 2003 Feb 21. PMID 12589803

    See all (42) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables protein kinase regulator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein kinase regulator activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein kinase regulator activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of protein kinase CK2 complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of protein kinase CK2 complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of protein kinase CK2 complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    casein kinase II beta2 subunit
    Names
    CG8914-PA
    CkIIbeta2-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      20289545..20290550
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_058059.4 → NP_477407.1  casein kinase II beta2 subunit [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_477407.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O96863, Q53XE8, Q9V919
      Related
      FBpp0085590
      Conserved Domains (1) summary
      pfam01214
      Location:9 → 189
      CK_II_beta; Casein kinase II regulatory subunit
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O96863.1 O96863

    Gene LinkOut

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