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    LysD Lysozyme D [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 38127, updated on 9-Dec-2024

    Summary

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    Official Symbol
    LysDprovided by FlyBase
    Official Full Name
    Lysozyme Dprovided by FlyBase
    Primary source
    FLYBASE:FBgn0004427
    Locus tag
    Dmel_CG9118
    See related
    AllianceGenome:FB:FBgn0004427
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG9118; Dmel\CG9118; Lys; lysD
    Summary
    Enables chitinase activity and lysozyme activity. Predicted to be involved in defense response to Gram-negative bacterium. Predicted to be located in extracellular space. Is expressed in adult heart; adult midgut; embryonic/larval anterior midgut; embryonic/larval midgut; and gastric caecum. Orthologous to human LYZ (lysozyme). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See LysD in Genome Data Viewer
    Location:
    61F3-61F3; 3-0 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (1210717..1211196, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (1210717..1211196, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene multiple wing hairs Neighboring gene uncharacterized protein Neighboring gene Lysozyme B Neighboring gene Lysozyme C Neighboring gene Lysozyme E Neighboring gene Lysozyme P

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The lysozyme locus in Drosophila melanogaster: different genes are expressed in midgut and salivary glands. Kylsten P, et al. Mol Gen Genet, 1992 Apr. PMID 1588905
    2. Translational and transcriptional control elements in the untranslated leader of the heat-shock gene hsp22. Hultmark D, et al. Cell, 1986 Feb 14. PMID 3943132
    3. Immune responsiveness in vector insects. Hoffmann JA. Proc Natl Acad Sci U S A, 1997 Oct 14. PMID 9326575, Free PMC Article
    4. The lysozyme locus in Drosophila melanogaster: an expanded gene family adapted for expression in the digestive tract. Daffre S, et al. Mol Gen Genet, 1994 Jan. PMID 8159165
    5. Insect lysozymes. Hultmark D. EXS, 1996. PMID 8765296

    See all (49) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables chitinase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables lysozyme activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables lysozyme activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables lysozyme activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in defense response to Gram-negative bacterium ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    located_in extracellular space ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    lysozyme D
    Names
    CG9118-PA
    LysD-PA
    lysozyme
    NP_476823.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      1210717..1211196 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_057475.3 → NP_476823.1  lysozyme D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_476823.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      C9QNX1, P29614, P37157, P83972, Q9W0J6, Q9W0J7
      Related
      FBpp0072530
      Conserved Domains (1) summary
      cd16899
      Location:19 → 139
      LYZ_C_invert; C-type invertebrate lysozyme
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P83972.1 P83972

    Gene LinkOut

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