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    List Lithium-inducible SLC6 transporter [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 37157, updated on 9-Dec-2024

    Summary

    Official Symbol
    Listprovided by FlyBase
    Official Full Name
    Lithium-inducible SLC6 transporterprovided by FlyBase
    Primary source
    FLYBASE:FBgn0034381
    Locus tag
    Dmel_CG15088
    See related
    AllianceGenome:FB:FBgn0034381
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG15088; Dmel\CG15088; DmNAT2; LIST
    Summary
    Predicted to enable L-amino acid transmembrane transporter activity; amino acid:sodium symporter activity; and neurotransmitter transmembrane transporter activity. Involved in response to lithium ion. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in adult brain; adult gut; adult head; and adult ventral nerve cord. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See List in Genome Data Viewer
    Location:
    55E10-55E10; 2-86 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (18727817..18730281, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (14615322..14617786, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR33942 Neighboring gene Heparan sulfate 3-O sulfotransferase-A Neighboring gene mir-4982 stem loop Neighboring gene long non-coding RNA:CR30121 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

    Interactions

    General gene information

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in amino acid transmembrane transport PubMed 
    involved_in glycine import across plasma membrane  
    involved_in neurotransmitter transport PubMed 
    involved_in response to lithium ion PubMed 
    involved_in sodium ion transmembrane transport  
    Component Evidence Code Pubs
    located_in membrane  
    located_in membrane PubMed 
    is_active_in plasma membrane  

    General protein information

    Preferred Names
    Lithium-inducible SLC6 transporter
    Names
    CG15088-PC
    CG15088-PD
    List-PC
    List-PD

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      18727817..18730281 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_176228.3 → NP_788408.2  Lithium-inducible SLC6 transporter, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_788408.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      A1ZBC8, Q86NQ1
      Conserved Domains (1) summary
      cd10324
      Location:19 → 351
      SLC6sbd; Solute carrier 6 family, neurotransmitter transporters; solute-binding domain
    2. NM_137520.4 → NP_611364.2  Lithium-inducible SLC6 transporter, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_611364.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      A1ZBC7, A9LRV7
      Conserved Domains (1) summary
      cd10324
      Location:19 → 489
      SLC6sbd; Solute carrier 6 family, neurotransmitter transporters; solute-binding domain
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