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    l(2)k05819 lethal (2) k05819 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 33644, updated on 4-Jan-2025

    Summary

    Official Symbol
    l(2)k05819provided by FlyBase
    Official Full Name
    lethal (2) k05819provided by FlyBase
    Primary source
    FLYBASE:FBgn0022153
    Locus tag
    Dmel_CG3054
    See related
    AllianceGenome:FB:FBgn0022153
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    anon-WO0140519.156; CG3054; Dmel\CG3054
    Summary
    Predicted to enable P-type magnesium transporter activity. Predicted to be involved in magnesium ion transport from cytosol to endoplasmic reticulum. Predicted to be active in endoplasmic reticulum membrane. Is expressed in adult head; embryonic/larval midgut; larval muscle system; and organism. Orthologous to human TMEM94 (transmembrane protein 94). [provided by Alliance of Genome Resources, Jan 2025]
    Orthologs
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    Genomic context

    See l(2)k05819 in Genome Data Viewer
    Location:
    24E5-24F1; 2-12 cM
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (4394196..4400487)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (4394196..4400487)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Partner of Sld Five 2 Neighboring gene Trehalose-6-phosphate synthase 1 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Dim1

    Genomic regions, transcripts, and products

    Interactions

    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables P-type magnesium transporter activity  
    enables molecular_function  
    Component Evidence Code Pubs
    is_active_in cellular_component  
    is_active_in endoplasmic reticulum membrane  

    General protein information

    Preferred Names
    lethal (2) k05819
    Names
    CG3054-PA
    CG3054-PC
    CG3054-PD
    l(2)k05819-PA
    l(2)k05819-PC
    l(2)k05819-PD

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      4394196..4400487
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001273094.1 → NP_001260023.1  lethal (2) k05819, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001260023.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7KU45
      Conserved Domains (1) summary
      cl02929
      Location:1224 → 1407
      Cation_ATPase_C; Cation transporting ATPase, C-terminus
    2. NM_164582.3 → NP_722974.1  lethal (2) k05819, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_722974.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VQZ1
      Related
      FBpp0077122
      Conserved Domains (1) summary
      cl02929
      Location:1239 → 1422
      Cation_ATPase_C; Cation transporting ATPase, C-terminus
    3. NM_134985.4 → NP_608829.2  lethal (2) k05819, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_608829.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7KU45
      Conserved Domains (1) summary
      cl02929
      Location:1224 → 1407
      Cation_ATPase_C; Cation transporting ATPase, C-terminus
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