Tb Tubby [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: Tbprovided by FlyBase
Official Full Name: Tubbyprovided by FlyBase
Primary source: FLYBASE:FBgn0243586
Locus tag: Dmel_CG5480
See related: AllianceGenome:FB:FBgn0243586
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: CG5480; Dmel\CG5480; Tu; TwdlA; Twdlalpha
Summary: Predicted to be a structural constituent of chitin-based larval cuticle. Predicted to be involved in body morphogenesis and chitin-based cuticle development. Predicted to be located in extracellular matrix. Predicted to be active in chitin-based extracellular matrix. Is expressed in dorsal head epidermis; embryonic dorsal epidermis; embryonic ventral epidermis; lateral head epidermis; and ventral head epidermis. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	3R	NT_033777.3 (26656440..26657531)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	3R	NT_033777.2 (22482162..22483253)

Chromosome 3R - NT_033777.3 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables structural constituent of chitin-based cuticle	ISS Inferred from Sequence or Structural Similarity more info
enables structural constituent of chitin-based larval cuticle	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in body morphogenesis	ISS Inferred from Sequence or Structural Similarity more info
involved_in chitin-based cuticle development	IBA Inferred from Biological aspect of Ancestor more info
involved_in chitin-based cuticle development	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
is_active_in chitin-based extracellular matrix	IBA Inferred from Biological aspect of Ancestor more info
located_in extracellular matrix	ISS Inferred from Sequence or Structural Similarity more info

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The following sections contain reference sequences that belong to a specific genome build. Explain