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    Rps2 ribosomal protein S2 [ Mus musculus (house mouse) ]

    Gene ID: 16898, updated on 9-Dec-2024

    Summary

    Official Symbol
    Rps2provided by MGI
    Official Full Name
    ribosomal protein S2provided by MGI
    Primary source
    MGI:MGI:105110
    See related
    Ensembl:ENSMUSG00000044533 AllianceGenome:MGI:105110
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    S4; Llrep3
    Summary
    A structural constituent of ribosome. Acts upstream of or within cellular response to interleukin-4. Part of cytosolic small ribosomal subunit. Is active in synapse. Is expressed in embryo; liver; and retina outer nuclear layer. Orthologous to human RPS2 (ribosomal protein S2). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in liver E14.5 (RPKM 886.9), liver E14 (RPKM 881.0) and 28 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Rps2 in Genome Data Viewer
    Location:
    17 A3.3; 17 12.51 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (24939037..24940901)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (24718121..24721927)

    Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene ring finger protein 151 Neighboring gene STARR-positive B cell enhancer ABC_E1190 Neighboring gene small nucleolar RNA, H/ACA box 7 Neighboring gene small nucleolar RNA host gene 9 Neighboring gene small nucleolar RNA, H/ACA box 64 Neighboring gene NADH:ubiquinone oxidoreductase subunit B10 Neighboring gene STARR-positive B cell enhancer ABC_E1936 Neighboring gene ribosomal protein L3-like

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Clone Names

    • MGC118037, MGC118038

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables enzyme binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables fibroblast growth factor binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables mRNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein-containing complex binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables structural constituent of ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables structural constituent of ribosome IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables structural constituent of ribosome ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within cellular response to interleukin-4 IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in cytoplasmic translation NAS
    Non-traceable Author Statement
    more info
    PubMed 
    involved_in positive regulation of ubiquitin-protein transferase activity ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in translation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm NAS
    Non-traceable Author Statement
    more info
    PubMed 
    located_in cytosol TAS
    Traceable Author Statement
    more info
     
    located_in cytosolic ribosome ISO
    Inferred from Sequence Orthology
    more info
     
    part_of cytosolic small ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of cytosolic small ribosomal subunit IDA
    Inferred from Direct Assay
    more info
    PubMed 
    part_of cytosolic small ribosomal subunit ISO
    Inferred from Sequence Orthology
    more info
     
    part_of cytosolic small ribosomal subunit NAS
    Non-traceable Author Statement
    more info
    PubMed 
    located_in nucleolus IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in postsynapse NAS
    Non-traceable Author Statement
    more info
    PubMed 
    part_of ribonucleoprotein complex ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in ribosome NAS
    Non-traceable Author Statement
    more info
    PubMed 
    is_active_in synapse EXP
    Inferred from Experiment
    more info
    PubMed 
    is_active_in synapse IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    small ribosomal subunit protein uS5
    Names
    40S ribosomal protein S2
    40S ribosomal protein S4
    protein LLRep3
    repeat family 3

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_008503.5NP_032529.2  small ribosomal subunit protein uS5

      See identical proteins and their annotated locations for NP_032529.2

      Status: VALIDATED

      Source sequence(s)
      AC154566, AK166664, BY443672
      Consensus CDS
      CCDS37493.1
      UniProtKB/Swiss-Prot
      P25444
      UniProtKB/TrEMBL
      Q3TL20, Q3TLE5, Q3TXS9, Q58EU3
      Related
      ENSMUSP00000131474.2, ENSMUST00000170715.8
      Conserved Domains (1) summary
      PTZ00070
      Location:54273
      PTZ00070; 40S ribosomal protein S2; Provisional

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000083.7 Reference GRCm39 C57BL/6J

      Range
      24939037..24940901
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)