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    CG17612 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 33639, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG17612provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0031597
    Locus tag
    Dmel_CG17612
    See related
    AllianceGenome:FB:FBgn0031597
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG17612
    Summary
    Predicted to enable DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Is expressed in embryonic brain; larval ventral nerve cord; and organism. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG17612 in Genome Data Viewer
    Location:
    24E4-24E4; 2-12 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (4380722..4382735, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (4380722..4382735, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR45363 Neighboring gene TNF-receptor-associated factor 4 Neighboring gene Vacuolar protein sorting 53 Neighboring gene Partner of Sld Five 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Drosophila homologs of mammalian TNF/TNFR-related molecules regulate segregation of Miranda/Prospero in neuroblasts. Wang H, et al. EMBO J, 2006 Dec 13. PMID 17139248, Free PMC Article
    2. A link between impaired purine nucleotide synthesis and apoptosis in Drosophila melanogaster. Holland C, et al. Genetics, 2011 Jun. PMID 21441212, Free PMC Article
    3. High resolution mapping of Twist to DNA in Drosophila embryos: Efficient functional analysis and evolutionary conservation. Ozdemir A, et al. Genome Res, 2011 Apr. PMID 21383317, Free PMC Article
    4. An RNA-interference screen in Drosophila to identify ZAD-containing C2H2 zinc finger genes that function in female germ cells. Shapiro-Kulnane L, et al. G3 (Bethesda), 2021 Jan 18. PMID 33561227, Free PMC Article
    5. ZAD-Domain Is Essential for Nuclear Localization of Insulator Proteins in Drosophila melanogaster. Zolotarev NA, et al. Acta Naturae, 2016 Jul-Sep. PMID 27795848, Free PMC Article

    See all (29) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables DNA-binding transcription factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables transcription cis-regulatory region binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of DNA-templated transcription ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG17612-PA
    CG17612-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      4380722..4382735 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_164581.2 → NP_722973.1  uncharacterized protein Dmel_CG17612, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_722973.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      I0E2I7, Q9VQY7
      Related
      FBpp0077152
      Conserved Domains (4) summary
      sd00017
      Location:359 → 379
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:323 → 343
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam07776
      Location:187 → 246
      zf-AD; Zinc-finger associated domain (zf-AD)
      pfam15909
      Location:356 → 438
      zf-C2H2_8; C2H2-type zinc ribbon

    2. NM_134980.2 → NP_608824.1  uncharacterized protein Dmel_CG17612, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_608824.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      I0E2I7, Q9VQY7
      Related
      FBpp0077153
      Conserved Domains (4) summary
      sd00017
      Location:359 → 379
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:323 → 343
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam07776
      Location:187 → 246
      zf-AD; Zinc-finger associated domain (zf-AD)
      pfam15909
      Location:356 → 438
      zf-C2H2_8; C2H2-type zinc ribbon
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VQY7 Q9VQY7

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