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    Fgop2 Fibroblast growth factor receptor 1 oncogene partner 2 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 33971, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Fgop2provided by FlyBase
    Official Full Name
    Fibroblast growth factor receptor 1 oncogene partner 2provided by FlyBase
    Primary source
    FLYBASE:FBgn0031871
    Locus tag
    Dmel_CG10158
    See related
    AllianceGenome:FB:FBgn0031871
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG10158; Dmel\CG10158; FGFR1OP2; FGOP2
    Summary
    Involved in negative regulation of hippo signaling. Part of FAR/SIN/STRIPAK complex. Is expressed in adult head and organism. Orthologous to several human genes including FGFR1OP2 (FGFR1 oncogene partner 2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Fgop2 in Genome Data Viewer
    Location:
    27C6-27C6; 2-23 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (6943178..6945289, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (6943178..6945289, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Heterogeneous nuclear ribonucleoprotein at 27C Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene interference hedgehog Neighboring gene Gas41

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in negative regulation of hippo signaling IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in negative regulation of hippo signaling IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in positive regulation of Ras protein signal transduction HGI PubMed 
    Component Evidence Code Pubs
    part_of FAR/SIN/STRIPAK complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    fibroblast growth factor receptor 1 oncogene partner 2
    Names
    CG10158-PA
    CG10158-PB
    Fgop2-PA
    Fgop2-PB
    fibroblast growth factor receptor 1 oncogene partner 2 ortholog

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      6943178..6945289 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001273242.1 → NP_001260171.1  fibroblast growth factor receptor 1 oncogene partner 2, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001260171.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9VM65
      UniProtKB/TrEMBL
      M9PEZ2
      Conserved Domains (1) summary
      pfam05769
      Location:3 → 181
      DUF837; Protein of unknown function (DUF837)

    2. NM_135240.4 → NP_609084.1  fibroblast growth factor receptor 1 oncogene partner 2, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_609084.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9VM65
      UniProtKB/TrEMBL
      M9PEZ2
      Related
      FBpp0078994
      Conserved Domains (1) summary
      pfam05769
      Location:3 → 181
      DUF837; Protein of unknown function (DUF837)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    M9PEZ2 M9PEZ2
    Q9VM65.1 Q9VM65

    Gene LinkOut

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