Cbp53E Calbindin 53E [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: Cbp53Eprovided by FlyBase
Official Full Name: Calbindin 53Eprovided by FlyBase
Primary source: FLYBASE:FBgn0004580
Locus tag: Dmel_CG6702
See related: AllianceGenome:FB:FBgn0004580
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: Calb; CALB2; CALB2/calretinin; cbn; Cbp33; cbp53E; CG6702; Dcbp; DCBP; Dcp; Dmel\CG6702
Summary: Predicted to enable calcium ion binding activity. Predicted to be involved in regulation of long-term synaptic potentiation and regulation of presynaptic cytosolic calcium ion concentration. Located in type II terminal bouton and type III terminal bouton. Is expressed in several structures, including NMJ bouton; central nervous system; ganglia; organism subdivision; and presumptive embryonic/larval system. Orthologous to several human genes including CALB2 (calbindin 2). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	2R	NT_033778.4 (16973927..16996057)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	2R	NT_033778.3 (12861432..12883562)

Chromosome 2R - NT_033778.4 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables calcium ion binding	IBA Inferred from Biological aspect of Ancestor more info
enables calcium ion binding	IEA Inferred from Electronic Annotation more info
enables calcium ion binding	TAS Traceable Author Statement more info	PubMed

Process	Evidence Code	Pubs
involved_in regulation of long-term synaptic potentiation	IBA Inferred from Biological aspect of Ancestor more info
involved_in regulation of presynaptic cytosolic calcium ion concentration	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in cytosol	IBA Inferred from Biological aspect of Ancestor more info
is_active_in dendrite	IBA Inferred from Biological aspect of Ancestor more info
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
is_active_in synapse	IBA Inferred from Biological aspect of Ancestor more info
is_active_in terminal bouton	IBA Inferred from Biological aspect of Ancestor more info
located_in type II terminal bouton	IDA Inferred from Direct Assay more info	PubMed
located_in type III terminal bouton	IDA Inferred from Direct Assay more info	PubMed

Names: CG6702-PA; CG6702-PB; Cbp53E-PA; Cbp53E-PB; calbindin; calbindin 32; calbindin-32; calretinin

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The following sections contain reference sequences that belong to a specific genome build. Explain