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    CG6465 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 41274, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG6465provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0037818
    Locus tag
    Dmel_CG6465
    See related
    AllianceGenome:FB:FBgn0037818
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG6465
    Summary
    Predicted to enable aminoacylase activity. Predicted to be involved in amino acid metabolic process. Predicted to be located in cytoplasm. Is expressed in several structures, including adult head; embryonic/larval midgut primordium; foregut primordium; posterior endoderm; and proventriculus primordium. Orthologous to human ACY1 (aminoacylase 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG6465 in Genome Data Viewer
    Location:
    86C4-86C4; 3-50 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (10675560..10677251, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (6501282..6502973, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene mir-4944 stem loop Neighboring gene homothorax Neighboring gene antisense RNA:CR44018 Neighboring gene long non-coding RNA:CR44230 Neighboring gene Phytanoyl-CoA dioxygenase domain containing 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Microarray analysis of juvenile hormone response in Drosophila melanogaster S2 cells. Willis DK, et al. J Insect Sci, 2010. PMID 20672983, Free PMC Article
    2. Drosophila as a diet discovery tool for treating amino acid disorders. Mele S, et al. Trends Endocrinol Metab, 2023 Feb. PMID 36567227
    3. siRNA screen identifies QPCT as a druggable target for Huntington's disease. Jimenez-Sanchez M, et al. Nat Chem Biol, 2015 May. PMID 25848931, Free PMC Article
    4. Genome-wide analysis in Drosophila reveals age-specific effects of SNPs on fitness traits. Durham MF, et al. Nat Commun, 2014 Jul 8. PMID 25000897
    5. Development of a Clickable Probe for Profiling of Protein Glutathionylation in the Central Cellular Metabolism of E. coli and Drosophila. Feng S, et al. Chem Biol, 2015 Nov 19. PMID 26526100

    See all (27) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables aminoacylase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables aminoacylase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in amino acid metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG6465-PA
    NP_650004.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      10675560..10677251 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_141747.3 → NP_650004.1  uncharacterized protein Dmel_CG6465 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_650004.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9I7K3
      Related
      FBpp0081799
      Conserved Domains (2) summary
      cd05646
      Location:8 → 399
      M20_AcylaseI_like; M20 Aminoacylase-I like subfamily
      TIGR01880
      Location:1 → 401
      Ac-peptdase-euk; N-acyl-L-amino-acid amidohydrolase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9I7K3 Q9I7K3

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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