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    CG15456 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 50123, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG15456provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0040650
    Locus tag
    Dmel_CG15456
    See related
    AllianceGenome:FB:FBgn0040650
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG15456
    Summary
    Predicted to be involved in negative regulation of apoptotic process and positive regulation of filopodium assembly. Predicted to be active in cytosol. Orthologous to human MIEN1 (migration and invasion enhancer 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG15456 in Genome Data Viewer
    Location:
    19D1-19D1; 1-64 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (20426431..20427042, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (20297458..20298069, complement)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene Protein phosphatase 19C Neighboring gene cactin Neighboring gene uncharacterized protein Neighboring gene maroon-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Drosophila p53 directs nonapoptotic programs in postmitotic tissue. Kurtz P, et al. Mol Biol Cell, 2019 May 15. PMID 30892991, Free PMC Article
    2. Ultra-deep sequencing of ribosome-associated poly-adenylated RNA in early Drosophila embryos reveals hundreds of conserved translated sORFs. Li H, et al. DNA Res, 2016 Dec. PMID 27559081, Free PMC Article
    3. Genes conserved in bilaterians but jointly lost with Myc during nematode evolution are enriched in cell proliferation and cell migration functions. Erives AJ. Dev Genes Evol, 2015 Sep. PMID 26173873, Free PMC Article
    4. Next-generation large-scale binary protein interaction network for Drosophila melanogaster. Tang HW, et al. Nat Commun, 2023 Apr 15. PMID 37061542, Free PMC Article
    5. CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans. Wei P, et al. Genome Res, 2020 Jan. PMID 31722958, Free PMC Article

    See all (23) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in negative regulation of apoptotic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in positive regulation of filopodium assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG15456-PA
    CG15456-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      20426431..20427042 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001298562.1 → NP_001285491.1  uncharacterized protein Dmel_CG15456, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001285491.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      B7FNM1, Q9VRA0
      Conserved Domains (1) summary
      TIGR02174
      Location:4 → 74
      CXXU_selWTH; selT/selW/selH selenoprotein domain

    2. NM_144035.3 → NP_652292.1  uncharacterized protein Dmel_CG15456, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_652292.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      B7FNM1, Q9VRA0
      Related
      FBpp0077015
      Conserved Domains (1) summary
      TIGR02174
      Location:4 → 74
      CXXU_selWTH; selT/selW/selH selenoprotein domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VRA0 Q9VRA0

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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