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    RpS19b Ribosomal protein S19b [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 42830, updated on 9-Dec-2024

    Summary

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    Official Symbol
    RpS19bprovided by FlyBase
    Official Full Name
    Ribosomal protein S19bprovided by FlyBase
    Primary source
    FLYBASE:FBgn0039129
    Locus tag
    Dmel_CG5338
    See related
    AllianceGenome:FB:FBgn0039129
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:SD22440; CG5338; Dmel\CG5338; rpS19; RpS19; RPS19b
    Summary
    Predicted to enable RNA binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in ribosomal small subunit assembly. Predicted to be located in ribosome. Predicted to be part of cytosolic small ribosomal subunit. Is expressed in adult head. Human ortholog(s) of this gene implicated in Diamond-Blackfan anemia and Diamond-Blackfan anemia 1. Orthologous to human RPS19 (ribosomal protein S19). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See RpS19b in Genome Data Viewer
    Location:
    95C13-95C13; 3-81 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (23932729..23933530, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (19758451..19759252, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Regulatory particle triple-A ATPase 2 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Glutamate dehydrogenase Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Oo-site: A dashboard to visualize gene expression during Drosophila oogenesis suggests meiotic entry is regulated post-transcriptionally. Martin ET, et al. Biol Open, 2022 May 15. PMID 35579517, Free PMC Article
    2. A feedback loop between heterochromatin and the nucleopore complex controls germ-cell-to-oocyte transition during Drosophila oogenesis. Sarkar K, et al. Dev Cell, 2023 Nov 20. PMID 37673064, Free PMC Article
    3. Ribosome heterogeneity and specialization in development. Norris K, et al. Wiley Interdiscip Rev RNA, 2021 Jul. PMID 33565275, Free PMC Article
    4. Eukaryotic ribosomal protein RPS25 interacts with the conserved loop region in a dicistroviral intergenic internal ribosome entry site. Nishiyama T, et al. Nucleic Acids Res, 2007. PMID 17287295, Free PMC Article
    5. Dynamic regulation of ribosome levels and translation during development. Breznak SM, et al. Semin Cell Dev Biol, 2023 Feb 28. PMID 35725716

    See all (52) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables structural constituent of ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables structural constituent of ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables structural constituent of ribosome TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cytoplasmic translation TAS
    Traceable Author Statement
    more info
    		 PubMed 
    involved_in ribosomal small subunit assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of cytosolic small ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of cytosolic small ribosomal subunit TAS
    Traceable Author Statement
    more info
    		 PubMed 
    located_in ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    ribosomal protein S19b
    Names
    CG5338-PB
    CG5338-PC
    RpS19b-PB
    RpS19b-PC
    ribosomal protein S19

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      23932729..23933530 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001275962.1 → NP_001262891.1  ribosomal protein S19b, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001262891.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q7KS38
      UniProtKB/TrEMBL
      A0A0B4KGR4
      Conserved Domains (1) summary
      pfam01090
      Location:5 → 138
      Ribosomal_S19e; Ribosomal protein S19e

    2. NM_142938.2 → NP_651195.1  ribosomal protein S19b, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_651195.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q7KS38
      UniProtKB/TrEMBL
      A0A0B4KGR4
      Related
      FBpp0083905
      Conserved Domains (1) summary
      pfam01090
      Location:5 → 138
      Ribosomal_S19e; Ribosomal protein S19e
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0A0B4KGR4 A0A0B4KGR4
    Q7KS38.3 Q7KS38

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
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