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    CG32944 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 40560, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG32944provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0052944
    Locus tag
    Dmel_CG32944
    See related
    AllianceGenome:FB:FBgn0052944
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG10532; CG9818; Dmel\CG32944
    Summary
    Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in intracellular signal transduction. Orthologous to human STK32A (serine/threonine kinase 32A); STK32B (serine/threonine kinase 32B); and STK32C (serine/threonine kinase 32C). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG32944 in Genome Data Viewer
    Location:
    82A6-82B1; 3-47.1 cM
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (4407227..4419578, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (232949..245300, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR45187 Neighboring gene lost Neighboring gene uncharacterized protein Neighboring gene spargel Neighboring gene uncharacterized protein Neighboring gene eukaryotic translation initiation factor 3 subunit a

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. DmGTSF1 is necessary for Piwi-piRISC-mediated transcriptional transposon silencing in the Drosophila ovary. Ohtani H, et al. Genes Dev, 2013 Aug 1. PMID 23913921, Free PMC Article
    2. Cross-species genetic screens to identify kinase targets for APP reduction in Alzheimer's disease. Huichalaf CH, et al. Hum Mol Genet, 2019 Jun 15. PMID 30753434, Free PMC Article
    3. A functional genomic analysis of cell morphology using RNA interference. Kiger AA, et al. J Biol, 2003. PMID 14527345, Free PMC Article
    4. CRISPR/Cas9 mediated genetic resource for unknown kinase and phosphatase genes in Drosophila. Wu M, et al. Sci Rep, 2020 Apr 30. PMID 32355295, Free PMC Article
    5. A whole-animal platform to advance a clinical kinase inhibitor into new disease space. Sonoshita M, et al. Nat Chem Biol, 2018 Mar. PMID 29355849, Free PMC Article

    See all (28) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    mobile_element

    • Loc: c4412704-4408473 mobile_element_type = transposon:Juan{}1190
    • Loc: c4414410-4414000 mobile_element_type = transposon:INE-1{}3803

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein serine/threonine kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in intracellular signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG32944-PE
    CG32944-PF
    CG32944-PG
    NP_001036666.2
    NP_001287157.1
    NP_788574.3

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      4407227..4419578 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001043201.5 → NP_001036666.2  uncharacterized protein Dmel_CG32944, isoform E [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001036666.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q0KID3
      Conserved Domains (2) summary
      smart00220
      Location:24 → 278
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd05578
      Location:23 → 283
      STKc_Yank1; Catalytic domain of the Serine/Threonine Kinase, Yank1

    2. NM_001300228.1 → NP_001287157.1  uncharacterized protein Dmel_CG32944, isoform G [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001287157.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q0KID3
      Conserved Domains (2) summary
      smart00220
      Location:24 → 278
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd05578
      Location:23 → 283
      STKc_Yank1; Catalytic domain of the Serine/Threonine Kinase, Yank1

    3. NM_176397.5 → NP_788574.3  uncharacterized protein Dmel_CG32944, isoform F [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_788574.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VN23
      Conserved Domains (2) summary
      smart00220
      Location:151 → 405
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd05578
      Location:150 → 410
      STKc_Yank1; Catalytic domain of the Serine/Threonine Kinase, Yank1
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q0KID3 Q0KID3
    Q9VN23 Q9VN23

    Gene LinkOut

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