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    CG3494 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 37903, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG3494provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0035008
    Locus tag
    Dmel_CG3494
    See related
    AllianceGenome:FB:FBgn0035008
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CT11751; Dmel\CG3494
    Summary
    Predicted to be involved in intracellular signal transduction. Predicted to be active in cytoplasm. Orthologous to human LRRC30 (leucine rich repeat containing 30). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG3494 in Genome Data Viewer
    Location:
    60D1-60D1; 2-107 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (24474299..24475261)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (20361822..20362784)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Lack of global meiotic sex chromosome inactivation, and paucity of tissue-specific gene expression on the Drosophila X chromosome. Mikhaylova LM, et al. BMC Biol, 2011 May 4. PMID 21542906, Free PMC Article
    2. The complex I subunit NDUFA10 selectively rescues Drosophila pink1 mutants through a mechanism independent of mitophagy. Pogson JH, et al. PLoS Genet, 2014 Nov. PMID 25412178, Free PMC Article
    3. Seizure suppression through manipulating splicing of a voltage-gated sodium channel. Lin WH, et al. Brain, 2015 Apr. PMID 25681415, Free PMC Article
    4. CRISPR/Cas9 mediated genetic resource for unknown kinase and phosphatase genes in Drosophila. Wu M, et al. Sci Rep, 2020 Apr 30. PMID 32355295, Free PMC Article
    5. Identification of Drosophila gene products required for phagocytosis of Candida albicans. Stroschein-Stevenson SL, et al. PLoS Biol, 2006 Jan. PMID 16336044, Free PMC Article

    See all (24) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in intracellular signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG3494-PA
    CG3494-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      24474299..24475261
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_138071.2 → NP_611915.1  uncharacterized protein Dmel_CG3494, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_611915.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q0E8W8
      Related
      FBpp0072202
      Conserved Domains (3) summary
      COG4886
      Location:34 → 231
      LRR; Leucine-rich repeat (LRR) protein [Transcription]
      sd00033
      Location:63 → 86
      LRR_RI; leucine-rich repeat [structural motif]
      pfam12799
      Location:85 → 124
      LRR_4; Leucine Rich repeats (2 copies)

    2. NM_166673.2 → NP_726449.1  uncharacterized protein Dmel_CG3494, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_726449.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q0E8W8
      Related
      FBpp0072203
      Conserved Domains (3) summary
      COG4886
      Location:34 → 231
      LRR; Leucine-rich repeat (LRR) protein [Transcription]
      sd00033
      Location:63 → 86
      LRR_RI; leucine-rich repeat [structural motif]
      pfam12799
      Location:85 → 124
      LRR_4; Leucine Rich repeats (2 copies)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q0E8W8 Q0E8W8

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