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    l(3)87Df lethal (3) 87Df [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 49762, updated on 9-Dec-2024

    Summary

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    Official Symbol
    l(3)87Dfprovided by FlyBase
    Official Full Name
    lethal (3) 87Dfprovided by FlyBase
    Primary source
    FLYBASE:FBgn0002354
    Locus tag
    Dmel_CG7620
    See related
    AllianceGenome:FB:FBgn0002354
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:SD27354; CG7620; COX20; Dmel\CG7620; l(3)s12; l(3)S12; S12
    Summary
    Predicted to be involved in mitochondrial cytochrome c oxidase assembly. Predicted to be located in mitochondrial inner membrane. Predicted to be active in mitochondrion. Is expressed in adult head and organism. Human ortholog(s) of this gene implicated in mitochondrial complex IV deficiency nuclear type 11. Orthologous to human COX20 (cytochrome c oxidase assembly factor COX20). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See l(3)87Df in Genome Data Viewer
    Location:
    87D9-87D9; 3-53 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (13030913..13031598)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (8856635..8857320)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene C-terminal Binding Protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene rosy Neighboring gene uncharacterized protein Neighboring gene snake

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Aberrant splicing and altered spatial expression patterns in fruitless mutants of Drosophila melanogaster. Goodwin SF, et al. Genetics, 2000 Feb. PMID 10655225, Free PMC Article
    2. Organization of the rosy locus in Drosophila melanogaster: evidence for a control element adjacent to the xanthine dehydrogenase structural element. Chovnick A, et al. Genetics, 1976 Oct. PMID 826445, Free PMC Article
    3. Aberrant splicing and transcription termination caused by P element insertion into the intron of a Drosophila gene. Horowitz H, et al. Genetics, 1995 Jan. PMID 7705633, Free PMC Article
    4. Vectors for P element-mediated gene transfer in Drosophila. Rubin GM, et al. Nucleic Acids Res, 1983 Sep 24. PMID 6312420, Free PMC Article
    5. Genetic analysis of the right (3') end of the rosy locus in Drosophila melanogaster. Clark SH, et al. Genet Res, 1986 Apr. PMID 3086181

    See all (58) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in mitochondrial cytochrome c oxidase assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in mitochondrial cytochrome c oxidase assembly IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in mitochondrial inner membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    lethal (3) 87Df
    Names
    CG7620-PA
    l(3)87Df-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      13030913..13031598
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_080203.2 → NP_524942.1  lethal (3) 87Df [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_524942.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q26251, Q9VG00
      Related
      FBpp0082171
      Conserved Domains (1) summary
      pfam12597
      Location:19 → 102
      DUF3767; Protein of unknown function (DUF3767)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q7JPT7 Q7JPT7
    Q9VG00 Q9VG00

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.