U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Non1 Novel nucleolar protein 1 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 35963, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    Non1provided by FlyBase
    Official Full Name
    Novel nucleolar protein 1provided by FlyBase
    Primary source
    FLYBASE:FBgn0028473
    Locus tag
    Dmel_CG8801
    See related
    AllianceGenome:FB:FBgn0028473
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:LD23830; CG30341; CG8801; Dmel\CG8801; LD23830
    Summary
    Predicted to enable GTPase activity and RNA binding activity. Predicted to be involved in ribosomal large subunit biogenesis. Located in nucleolus. Is expressed in adult head and organism. Orthologous to human GTPBP4 (GTP binding protein 4). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See Non1 in Genome Data Viewer
    Location:
    45D2-45D3; 2-60 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (9396265..9398734, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (5283770..5286239, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene lethal (2) 03659 Neighboring gene Outer dynein arm dynein axonemal light chain 1 Neighboring gene lethal (2) k10201 Neighboring gene uncharacterized protein Neighboring gene wunen

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Dynamic regulation of ribosome levels and translation during development. Breznak SM, et al. Semin Cell Dev Biol, 2023 Feb 28. PMID 35725716
    2. A translation control module coordinates germline stem cell differentiation with ribosome biogenesis during Drosophila oogenesis. Martin ET, et al. Dev Cell, 2022 Apr 11. PMID 35413237, Free PMC Article
    3. Identification of a suppressor of retinal degeneration in Drosophila photoreceptors. Georgiev P, et al. J Neurogenet, 2012 Sep. PMID 23043643
    4. Hangover Links Nuclear RNA Signaling to cAMP Regulation via the Phosphodiesterase 4d Ortholog dunce. Ruppert M, et al. Cell Rep, 2017 Jan 10. PMID 28076795
    5. A survey of ovary-, testis-, and soma-biased gene expression in Drosophila melanogaster adults. Parisi M, et al. Genome Biol, 2004. PMID 15186491, Free PMC Article

    See all (40) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables GTP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables GTPase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables GTPase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in ribosomal large subunit biogenesis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in ribosomal large subunit biogenesis ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleolus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleolus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus HDA PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    putative nucleolar protein 1
    Names
    CG8801-PA
    CG8801-PB
    Non1-PA
    Non1-PB

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      9396265..9398734 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001299318.1 → NP_001286247.1  putative nucleolar protein 1, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001286247.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9V411
      UniProtKB/TrEMBL
      A0A0B4LEY9, C5WLT8
      Conserved Domains (3) summary
      cd01897
      Location:169 → 341
      NOG; Nucleolar GTP-binding protein (NOG)
      COG1084
      Location:5 → 341
      Nog1; GTP-binding protein, GTP1/Obg family [General function prediction only]
      pfam08155
      Location:398 → 448
      NOGCT; NOGCT (NUC087) domain

    2. NM_136640.5 → NP_610484.1  putative nucleolar protein 1, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_610484.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9V411
      UniProtKB/TrEMBL
      A0A0B4LEY9, C5WLT8
      Related
      FBpp0087637
      Conserved Domains (3) summary
      cd01897
      Location:169 → 341
      NOG; Nucleolar GTP-binding protein (NOG)
      COG1084
      Location:5 → 341
      Nog1; GTP-binding protein, GTP1/Obg family [General function prediction only]
      pfam08155
      Location:398 → 448
      NOGCT; NOGCT (NUC087) domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0A0B4LEY9 A0A0B4LEY9
    Q9V411.1 Q9V411

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
    Chemical Information
    Molecular Biology Databases
    Research Materials
    Tools